EPIC-Norfolk Publications Database

Immunodeficiency, autoimmunity, and increased risk of B cell malignancy in humans with mutations.

Rae W, Sowerby JM, Verhoeven D, Youssef M, Kotagiri P, Savinykh N, Coomber EL, Boneparth A, Chan A, Gong C, Jansen MH, du Long R, Santilli G, Simeoni I, Stephens J, Wu K, Zinicola M, Allen HL, Baxendale H, Kumararatne D, Gkrania-Klotsas E, Scheffler Mendoza SC, Yamazaki-Nakashimada MA, Ruiz LB, Rojas-Maruri CM, Lugo Reyes SO, Lyons PA, Williams AP, Hodson DJ, Bishop GA, Thrasher AJ, Thomas DC, Murphy MP, Vyse TJ, Milner JD, Kuijpers TW, and Smith KGC

Science immunology. Aug 2022

(DOI : 10.1126/sciimmunol.abn3800)

Pre-diagnostic C-reactive protein concentrations, CRP genetic variation and mortality among individuals with colorectal cancer in Western European populations.

Nimptsch K, Aleksandrova K, Fedirko V, Jenab M, Gunter MJ, Siersema PD, Wu K, Katzke V, Kaaks R, Panico S, Palli D, May AM, Sieri S, Bueno-de-Mesquita B, Standahl K, Sánchez MJ, Perez-Cornago A, Olsen A, Tjønneland A, Bonet CB, Dahm CC, Chirlaque MD, Fiano V, Tumino R, Gurrea AB, Boutron-Ruault MC, Menegaux F, Severi G, Van Guelpen B, Lee YA, and Pischon T

BMC cancer. Dec 2021

(DOI : 10.1186/s12885-022-09778-9)

Polyclonal human antibodies against glycans bearing red meat-derived non-human sialic acid N-glycolylneuraminic acid are stable, reproducible, complex and vary between individuals: Total antibody levels are associated with colorectal cancer risk.

Samraj AN, Bertrand KA, Luben R, Khedri Z, Yu H, Nguyen D, Gregg CJ, Diaz SL, Sawyer S, Chen X, Eliassen H, Padler-Karavani V, Wu K, Khaw KT, Willett W, and Varki A

PLoS ONE. Jan 2018

(DOI : 10.1371/journal.pone.0197464)

Genetic variation in the ADIPOQ gene, adiponectin concentrations and risk of colorectal cancer: a Mendelian Randomization analysis using data from three large cohort studies.

Nimptsch K, Song M, Aleksandrova K, Katsoulis M, Freisling H, Jenab M, Gunter MJ, Tsilidis KK, Weiderpass E, Bueno-de-Mesquita HB, Chong DQ, Jensen MK, Wu C, Overvad K, Kühn T, Barrdahl M, Melander O, Jirström K, Peeters PH, Sieri S, Panico S, Cross AJ, Riboli E, Van Guelpen B, Myte R, Huerta JM, Rodriguez-Barranco M, Quirós JR, Dorronsoro M, Tjønneland A, Olsen A, Travis R, Boutron-Ruault MC, Carbonnel F, Severi G, Bonet C, Palli D, Janke J, Lee YA, Boeing H, Giovannucci EL, Ogino S, Fuchs CS, Rimm E, Wu K, Chan AT, and Pischon T

European Journal of Epidemiology. Nov 2016

(DOI : 10.1007/s10654-017-0262-y)

A single nucleotide polymorphism in the 3-hydroxy-3-methylglutaryl-coenzyme A reductase gene ( HMGCR) influences the serum triacylglycerol relationship with dietary fat and fibre in the European Prospective Investigation into Cancer and Nutrition in Norfolk (EPIC-Norfolk) study.

Freitas RN, Khaw KT, Wu K, Bowman R, Jeffery H, Luben R, Wareham NJ, and Bingham SA

The British journal of nutrition. Jun 2010

(DOI : 10.1017/S0007114510001145)

HMGCR gene polymorphism is associated with stroke risk in the EPIC-Norfolk study.

Freitas RN, Khaw KT, Wu K, Bowman R, Jeffery H, Luben R, Wareham NJ, and Rodwell S

European journal of cardiovascular prevention and rehabilitation : official journal of the European Society of Cardiology, Working Groups on Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology. Nov 2009

(DOI : 10.1097/HJR.0b013e328330be77)

A HMGCR polymorphism is associated with relations between blood pressure and urinary sodium and potassium ratio in the Epic-Norfolk Study.

Freitas RN, Khaw KT, Wu K, Bowman R, Jeffery H, Luben R, Wareham NJ, and Bingham SA

Journal of the American Society of Hypertension : JASH. Mar 2009

(DOI : 10.1016/j.jash.2009.05.001)

Apolipoprotein E polymorphisms, dietary fat and fibre, and serum lipids: the EPIC Norfolk study.

Wu K, Bowman R, Welch AA, Luben RN, Wareham NJ, Khaw KT, and Bingham SA

European heart journal. Nov 2007

(DOI : 10.1093/eurheartj/ehm482)