EPIC-Norfolk Publications Database

Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association. Aug 2017

(DOI : 10.1093/ndt/gfy071)

Carotenoid dietary intakes and plasma concentrations are associated with heel bone ultrasound attenuation and osteoporotic fracture risk in the European Prospective Investigation into Cancer and Nutrition (EPIC)-Norfolk cohort.

Hayhoe RPG, Lentjes MAH, Mulligan AA, Luben RN, Khaw KT, and Welch AA

The British journal of nutrition. Jun 2017

(DOI : 10.1017/S0007114517001180)

Cross-sectional associations of dietary and circulating magnesium with skeletal muscle mass in the EPIC-Norfolk cohort.

Hayhoe RPG, Lentjes MAH, Mulligan AA, Luben RN, Khaw KT, and Welch AA

Clinical nutrition (Edinburgh, Scotland). Apr 2017

(DOI : 10.1016/j.clnu.2018.01.014)

Weight change and 15 year mortality: results from the European Prospective Investigation into Cancer in Norfolk (EPIC-Norfolk) cohort study.

Mulligan AA, Lentjes MAH, Luben RN, Wareham NJ, and Khaw KT

European Journal of Epidemiology. Feb 2017

(DOI : 10.1007/s10654-017-0343-y)

Thyroid Function Tests in the Reference Range and Fracture: Individual Participant Analysis of Prospective Cohorts.

Aubert CE, Floriani C, Bauer DC, da Costa BR, Segna D, Blum MR, Collet TH, Fink HA, Cappola AR, Syrogiannouli L, Peeters RP, Åsvold BO, den Elzen WPJ, Luben RN, Bremner AP, Gogakos A, Eastell R, Kearney PM, Hoff M, Le Blanc E, Ceresini G, Rivadeneira F, Uitterlinden AG, Khaw KT, Langhammer A, Stott DJ, Westendorp RGJ, Ferrucci L, Williams GR, Gussekloo J, Walsh JP, Aujesky D, Rodondi N, and Thyroid Studies Collaboration Thyroid Studies Collaboration

The Journal of clinical endocrinology and metabolism. Jan 2017

(DOI : 10.1210/jc.2017-00294)

Thyroid Function Within the Reference Range and the Risk of Stroke: An Individual Participant Data Analysis.

Chaker L, Baumgartner C, den Elzen WP, Collet TH, Ikram MA, Blum MR, Dehghan A, Drechsler C, Luben RN, Portegies ML, Iervasi G, Medici M, Stott DJ, Dullaart RP, Ford I, Bremner A, Newman AB, Wanner C, Sgarbi JA, Dörr M, Longstreth WT, Psaty BM, Ferrucci L, Maciel RM, Westendorp RG, Jukema JW, Ceresini G, Imaizumi M, Hofman A, Bakker SJ, Franklyn JA, Khaw KT, Bauer DC, Walsh JP, Razvi S, Gussekloo J, Völzke H, Franco OH, Cappola AR, Rodondi N, Peeters RP, and Thyroid Studies Collaboration Thyroid Studies Collaboration

The Journal of clinical endocrinology and metabolism. Nov 2016

(DOI : 10.1210/jc.2016-2255)

ω-3 Polyunsaturated Fatty Acid Biomarkers and Coronary Heart Disease: Pooling Project of 19 Cohort Studies.

Del Gobbo LC, Imamura F, Aslibekyan S, Marklund M, Virtanen JK, Wennberg M, Frazier-Wood AC, Fretts AM, Guallar E, Prem K, Tanaka T, Zhou X, Helmer C, Ingelsson E, Yuan JM, Campos H, Djoussé L, Giles GG, Hu FB, Jansson JH, Johansson I, Khaw KT, Koh WP, Lemaitre RN, Lind L, Luben RN, Rimm EB, Riserus U, Samieri C, Franks PW, Siscovick DS, Stampfer M, Steffen LM, Steffen BT, Tsai MY, van Dam RM, Voutilainen S, Willett WC, Woodward M, and Mozaffarian D

JAMA internal medicine. Jul 2016

(DOI : 10.1001/jamainternmed.2016.2925)

Fatigue is associated with excess mortality in the general population: results from the EPIC-Norfolk study.

Basu N, Yang X, Luben RN, Whibley D, Macfarlane GJ, Wareham NJ, Khaw KT, and Myint PK

BMC medicine. May 2016

(DOI : 10.1186/s12916-016-0662-y)

New insights into the genetics of primary open-angle glaucoma based on meta-analyses of intraocular pressure and optic disc characteristics.

Springelkamp H, Iglesias AI, Mishra A, Höhn R, Wojciechowski R, Khawaja AP, Nag A, Wang YX, Wang JJ, Cuellar-Partida G, Gibson J, Bailey JN, Vithana EN, Gharahkhani P, Boutin T, Ramdas WD, Zeller T, Luben RN, Yonova-Doing E, Viswanathan AC, Yazar S, Cree AJ, Haines JL, Koh JY, Souzeau E, Wilson JF, Amin N, Müller C, Venturini C, Kearns LS, Kang JH, NEIGHBORHOOD Consortium NEIGHBORHOOD Consortium, Tham YC, Zhou T, van Leeuwen EM, Nickels S, Sanfilippo P, Liao J, van der Linde H, Zhao W, van Koolwijk LM, Zheng L, Rivadeneira F, Baskaran M, van der Lee SJ, Perera S, de Jong PT, Oostra BA, Uitterlinden AG, Fan Q, Hofman A, Tai ES, Vingerling JR, Sim X, Wolfs RC, Teo YY, Lemij HG, Khor CC, Willemsen R, Lackner KJ, Aung T, Jansonius NM, Montgomery G, Wild PS, Young TL, Burdon KP, Hysi PG, Pasquale LR, Wong TY, Klaver CC, Hewitt AW, Jonas JB, Mitchell P, Lotery AJ, Foster PJ, Vitart V, Pfeiffer N, Craig JE, Mackey DA, Hammond CJ, Wiggs JL, Cheng CY, van Duijn CM, and MacGregor S

Human Molecular Genetics. May 2016

(DOI : 10.1093/hmg/ddw399)

Genome-wide association reveals that common genetic variation in the kallikrein-kinin system is associated with serum L-arginine levels.

Zhang W, Chen MH, Luben RN, Scott WR, Scott J, Khaw KT, van der Harst P, Wareham NJ, Vasan RS, Chambers JC, and Kooner JS

Thrombosis and haemostasis. Feb 2016

(DOI : 10.1160/TH16-02-0151)

Reply to W Lin and R Wang.

Hayhoe RP, Lentjes MA, Luben RN, Khaw KT, and Welch AA

The American Journal of Clinical Nutrition. Jan 2016

(DOI : 10.3945/ajcn.115.122291)

Associations with intraocular pressure across Europe: The European Eye Epidemiology (E) Consortium.

Khawaja AP, Springelkamp H, Creuzot-Garcher C, Delcourt C, Hofman A, Höhn R, Iglesias AI, Wolfs RC, Korobelnik JF, Silva R, Topouzis F, Williams KM, Bron AM, Buitendijk GH, Cachulo MD, Cougnard-Gregoire A, Dartigues JF, Hammond CJ, Pfeiffer N, Salonikiou A, van Duijn CM, Vingerling JR, Luben RN, Mirshahi A, Lamparter J, Klaver CC, Jansonius NM, Foster PJ, and European Eye Epidemiology (E³) Consortium

European Journal of Epidemiology. Jan 2016

(DOI : 10.1007/s10654-016-0191-1)

RAD51B in Familial Breast Cancer.

Pelttari LM, Khan S, Vuorela M, Kiiski JI, Vilske S, Nevanlinna V, Ranta S, Schleutker J, Winqvist R, Kallioniemi A, Dörk T, Bogdanova NV, Figueroa J, Pharoah PD, Schmidt MK, Dunning AM, García-Closas M, Bolla MK, Dennis J, Michailidou K, Wang Q, Hopper JL, Southey MC, Rosenberg EH, Fasching PA, Beckmann MW, Peto J, Dos-Santos-Silva I, Sawyer EJ, Tomlinson I, Burwinkel B, Surowy H, Guénel P, Truong T, Bojesen SE, Nordestgaard BG, Benitez J, González-Neira A, Neuhausen SL, Anton-Culver H, Brenner H, Arndt V, Meindl A, Schmutzler RK, Brauch H, Brüning T, Lindblom A, Margolin S, Mannermaa A, Hartikainen JM, Chenevix-Trench G, kConFab/AOCS Investigators kConFab/AOCS Investigators, Van Dyck L, Janssen H, Chang-Claude J, Rudolph A, Radice P, Peterlongo P, Hallberg E, Olson JE, Giles GG, Milne RL, Haiman CA, Schumacher F, Simard J, Dumont M, Kristensen V, Borresen-Dale AL, Zheng W, Beeghly-Fadiel A, Grip M, Andrulis IL, Glendon G, Devilee P, Seynaeve C, Hooning MJ, Collée M, Cox A, Cross SS, Shah M, Luben RN, Hamann U, Torres D, Jakubowska A, Lubinski J, Couch FJ, Yannoukakos D, Orr N, Swerdlow A, Darabi H, Li J, Czene K, Hall P, Easton DF, Mattson J, Blomqvist C, Aittomäki K, and Nevanlinna H

PLoS ONE. Oct 2015

(DOI : 10.1371/journal.pone.0153788)

Habitual chocolate consumption and the risk of incident heart failure among healthy men and women.

Kwok CS, Loke YK, Welch AA, Luben RN, Lentjes MA, Boekholdt SM, Pfister R, Mamas MA, Wareham NJ, Khaw KT, and Myint PK

Nutrition, metabolism, and cardiovascular diseases : NMCD. Oct 2015

(DOI : 10.1016/j.numecd.2016.01.003)

Investigating Physical Activity in the Etiology of Pancreatic Cancer: The Age at Which This Is Measured Is Important and Is Independent of Body Mass Index.

Noor NM, Banim PJ, Luben RN, Khaw KT, and Hart AR

Pancreas. Sep 2015

(DOI : 10.1097/MPA.0000000000000494)

No evidence that protein truncating variants in BRIP1 are associated with breast cancer risk: implications for gene panel testing.

Easton DF, Lesueur F, Decker B, Michailidou K, Li J, Allen J, Luccarini C, Pooley KA, Shah M, Bolla MK, Wang Q, Dennis J, Ahmad J, Thompson ER, Damiola F, Pertesi M, Voegele C, Mebirouk N, Robinot N, Durand G, Forey N, Luben RN, Ahmed S, Aittomäki K, Anton-Culver H, Arndt V, Australian Ovarian Cancer Study Group, Baynes C, Beckman MW, Benitez J, Van Den Berg D, Blot WJ, Bogdanova NV, Bojesen SE, Brenner H, Chang-Claude J, Chia KS, Choi JY, Conroy DM, Cox A, Cross SS, Czene K, Darabi H, Devilee P, Eriksson M, Fasching PA, Figueroa J, Flyger H, Fostira F, García-Closas M, Giles GG, Glendon G, González-Neira A, Guénel P, Haiman CA, Hall P, Hart SN, Hartman M, Hooning MJ, Hsiung CN, Ito H, Jakubowska A, James PA, John EM, Johnson N, Jones M, Kabisch M, Kang D, kConFab Investigators kConFab Investigators, Kosma VM, Kristensen V, Lambrechts D, Li N, Lifepool Investigators Lifepool Investigators, Lindblom A, Long J, Lophatananon A, Lubinski J, Mannermaa A, Manoukian S, Margolin S, Matsuo K, Meindl A, Mitchell G, Muir K, NBCS Investigators NBCS Investigators, Nevelsteen I, van den Ouweland A, Peterlongo P, Phuah SY, Pylkäs K, Rowley SM, Sangrajrang S, Schmutzler RK, Shen CY, Shu XO, Southey MC, Surowy H, Swerdlow A, Teo SH, Tollenaar RA, Tomlinson I, Torres D, Truong T, Vachon C, Verhoef S, Wong-Brown M, Zheng W, Zheng Y, Nevanlinna H, Scott RJ, Andrulis IL, Wu AH, Hopper JL, Couch FJ, Winqvist R, Burwinkel B, Sawyer EJ, Schmidt MK, Rudolph A, Dörk T, Brauch H, Hamann U, Neuhausen SL, Milne RL, Fletcher O, Pharoah PD, Campbell IG, Dunning AM, Le Calvez-Kelm F, Goldgar DE, Tavtigian SV, and Chenevix-Trench G

Journal of medical genetics. Sep 2015

(DOI : 10.1136/jmedgenet-2015-103529)

Long-term mortality of hospitalized pneumonia in the EPIC-Norfolk cohort.

Myint PK, Hawkins KR, Clark AB, Luben RN, Wareham NJ, Khaw KT, and Wilson AM

Epidemiology and infection. Aug 2015

(DOI : 10.1017/S0950268815001971)

Subclinical thyroid dysfunction and fracture risk: a meta-analysis.

Blum MR, Bauer DC, Collet TH, Fink HA, Cappola AR, da Costa BR, Wirth CD, Peeters RP, Åsvold BO, den Elzen WP, Luben RN, Imaizumi M, Bremner AP, Gogakos A, Eastell R, Kearney PM, Strotmeyer ES, Wallace ER, Hoff M, Ceresini G, Rivadeneira F, Uitterlinden AG, Stott DJ, Westendorp RG, Khaw KT, Langhammer A, Ferrucci L, Gussekloo J, Williams GR, Walsh JP, Jüni P, Aujesky D, Rodondi N, and Thyroid Studies Collaboration Thyroid Studies Collaboration

JAMA. May 2015

(DOI : 10.1001/jama.2015.5161)

Ideal cardiovascular health and risk of cardiovascular events in the EPIC-Norfolk prospective population study.

Lachman S, Peters RJ, Lentjes MA, Mulligan AA, Luben RN, Wareham NJ, Khaw KT, and Boekholdt SM

European Journal of Preventive Cardiology. May 2015

(DOI : 10.1177/2047487315602015)

Subclinical Hypothyroidism and the Risk of Stroke Events and Fatal Stroke: An Individual Participant Data Analysis.

Chaker L, Baumgartner C, den Elzen WP, Ikram MA, Blum MR, Collet TH, Bakker SJ, Dehghan A, Drechsler C, Luben RN, Hofman A, Portegies ML, Medici M, Iervasi G, Stott DJ, Ford I, Bremner A, Wanner C, Ferrucci L, Newman AB, Dullaart RP, Sgarbi JA, Ceresini G, Maciel RM, Westendorp RG, Jukema JW, Imaizumi M, Franklyn JA, Bauer DC, Walsh JP, Razvi S, Khaw KT, Cappola AR, Völzke H, Franco OH, Gussekloo J, Rodondi N, Peeters RP, and Thyroid Studies Collaboration Thyroid Studies Collaboration

The Journal of clinical endocrinology and metabolism. Apr 2015

(DOI : 10.1210/jc.2015-1438)

The relationship between dietary magnesium intake, stroke and its major risk factors, blood pressure and cholesterol, in the EPIC-Norfolk cohort.

Bain LK, Myint PK, Jennings A, Lentjes MA, Luben RN, Khaw KT, Wareham NJ, and Welch AA

International journal of cardiology. Mar 2015

(DOI : 10.1016/j.ijcard.2015.05.166)

Flavonoid intake in European adults (18 to 64 years).

Vogiatzoglou A, Mulligan AA, Lentjes MA, Luben RN, Spencer JP, Schroeter H, Khaw KT, and Kuhnle GG

PLoS ONE. Mar 2015

(DOI : 10.1371/journal.pone.0128132)

Association between sucrose intake and risk of overweight and obesity in a prospective sub-cohort of the European Prospective Investigation into Cancer in Norfolk (EPIC-Norfolk).

Kuhnle GG, Tasevska N, Lentjes MA, Griffin JL, Sims MA, Richardson L, Aspinall SM, Mulligan AA, Luben RN, and Khaw KT

Public Health Nutrition. Feb 2015

(DOI : 10.1017/S1368980015000300)

Meta-analysis of gene-environment-wide association scans accounting for education level identifies additional loci for refractive error.

Fan Q, Verhoeven VJ, Wojciechowski R, Barathi VA, Hysi PG, Guggenheim JA, Höhn R, Vitart V, Khawaja AP, Yamashiro K, Hosseini SM, Lehtimäki T, Lu Y, Haller T, Xie J, Delcourt C, Pirastu M, Wedenoja J, Gharahkhani P, Venturini C, Miyake M, Hewitt AW, Guo X, Mazur J, Huffman JE, Williams KM, Polasek O, Campbell H, Rudan I, Vatavuk Z, Wilson JF, Joshi PK, McMahon G, St Pourcain B, Evans DM, Simpson CL, Schwantes-An TH, Igo RP, Mirshahi A, Cougnard-Gregoire A, Bellenguez C, Blettner M, Raitakari O, Kähönen M, Seppala I, Zeller T, Meitinger T, Consortium for Refractive Error and Myopia, Ried JS, Gieger C, Portas L, van Leeuwen EM, Amin N, Uitterlinden AG, Rivadeneira F, Hofman A, Vingerling JR, Wang YX, Wang X, Tai-Hui Boh E, Ikram MK, Sabanayagam C, Gupta P, Tan V, Zhou L, Ho CE, Lim W, Beuerman RW, Siantar R, Tai ES, Vithana E, Mihailov E, Khor CC, Hayward C, Luben RN, Foster PJ, Klein BE, Klein R, Wong HS, Mitchell P, Metspalu A, Aung T, Young TL, He M, Pärssinen O, van Duijn CM, Jin Wang J, Williams C, Jonas JB, Teo YY, Mackey DA, Oexle K, Yoshimura N, Paterson AD, Pfeiffer N, Wong TY, Baird PN, Stambolian D, Wilson JE, Cheng CY, Hammond CJ, Klaver CC, Saw SM, Rahi JS, Korobelnik JF, Kemp JP, Timpson NJ, Smith GD, Craig JE, Burdon KP, Fogarty RD, Iyengar SK, Chew E, Janmahasatian S, Martin NG, MacGregor S, Xu L, Schache M, Nangia V, Panda-Jonas S, Wright AF, Fondran JR, Lass JH, Feng S, Zhao JH, Khaw KT, Wareham NJ, Rantanen T, Kaprio J, Pang CP, Chen LJ, Tam PO, Jhanji V, Young AL, Döring A, Raffel LJ, Cotch MF, Li X, Yip SP, Yap MK, Biino G, Vaccargiu S, Fossarello M, Fleck B, Yazar S, Tideman JW, Tedja M, Deangelis MM, Morrison M, Farrer L, Zhou X, Chen W, Mizuki N, Meguro A, and Mäkelä KM

Nature communications. Feb 2015

(DOI : 10.1038/ncomms11008)

Longitudinal association of C-reactive protein and Haemoglobin A1c over 13 years: the European Prospective Investigation into Cancer--Norfolk study.

Ahmadi-Abhari S, Kaptoge S, Luben RN, Wareham NJ, and Khaw KT

Cardiovascular diabetology. Jan 2015

(DOI : 10.1186/s12933-015-0224-1)

Total anticholinergic burden and risk of mortality and cardiovascular disease over 10 years in 21,636 middle-aged and older men and women of EPIC-Norfolk prospective population study.

Myint PK, Kwok CS, Luben RN, Wareham NJ, and Khaw KT

Age and ageing. Nov 2014

(DOI : 10.1093/ageing/afu185)

Dietary magnesium and potassium intakes and circulating magnesium are associated with heel bone ultrasound attenuation and osteoporotic fracture risk in the EPIC-Norfolk cohort study.

Hayhoe RP, Lentjes MA, Luben RN, Khaw KT, and Welch AA

The American Journal of Clinical Nutrition. Nov 2014

(DOI : 10.3945/ajcn.114.102723)

Habitual chocolate consumption and risk of cardiovascular disease among healthy men and women.

Kwok CS, Boekholdt SM, Lentjes MA, Loke YK, Luben RN, Yeong JK, Wareham NJ, Myint PK, and Khaw KT

Heart (British Cardiac Society). Oct 2014

(DOI : 10.1136/heartjnl-2014-307050)

Associations between flavan-3-ol intake and CVD risk in the Norfolk cohort of the European Prospective Investigation into Cancer (EPIC-Norfolk).

Vogiatzoglou A, Mulligan AA, Bhaniani A, Lentjes MAH, McTaggart A, Luben RN, Heiss C, Kelm M, Merx MW, Spencer JPE, Schroeter H, Khaw KT, and Kuhnle GGC

Free radical biology & medicine. Oct 2014

(DOI : 10.1016/j.freeradbiomed.2015.03.005)

Contribution of cod liver oil-related nutrients (vitamins A, D, E and eicosapentaenoic acid and docosahexaenoic acid) to daily nutrient intake and their associations with plasma concentrations in the EPIC-Norfolk cohort.

Lentjes MA, Mulligan AA, Welch AA, Bhaniani A, Luben RN, and Khaw KT

Journal of human nutrition and dietetics : the official journal of the British Dietetic Association. Sep 2014

(DOI : 10.1111/jhn.12271)

Cod liver oil supplement consumption and health: cross-sectional results from the EPIC-Norfolk cohort study.

Lentjes MA, Welch AA, Mulligan AA, Luben RN, Wareham NJ, and Khaw KT

Nutrients. Aug 2014

(DOI : 10.3390/nu6104320)

Prevalence of refractive error in Europe: the European Eye Epidemiology (E(3)) Consortium.

Williams KM, Verhoeven VJ, Cumberland P, Bertelsen G, Wolfram C, Buitendijk GH, Hofman A, van Duijn CM, Vingerling JR, Kuijpers RW, Höhn R, Mirshahi A, Khawaja AP, Luben RN, Erke MG, von Hanno T, Mahroo O, Hogg R, Gieger C, Cougnard-Gregoire A, Anastasopoulos E, Bron A, Dartigues JF, Korobelnik JF, Creuzot-Garcher C, Topouzis F, Delcourt C, Rahi J, Meitinger T, Fletcher A, Foster PJ, Pfeiffer N, Klaver CC, and Hammond CJ

European Journal of Epidemiology. Aug 2014

(DOI : 10.1007/s10654-015-0010-0)

FTO genetic variants, dietary intake and body mass index: insights from 177,330 individuals.

Qi Q, Kilpeläinen TO, Downer MK, Tanaka T, Smith CE, Sluijs I, Sonestedt E, Chu AY, Renstrom F, Lin X, Ängquist LH, Huang J, Liu Z, Li Y, Asif Ali M, Xu M, Ahluwalia TS, Boer JM, Chen P, Daimon M, Eriksson J, Perola M, Friedlander Y, Gao YT, Heppe DH, Holloway JW, Houston DK, Kanoni S, Kim YM, Laaksonen MA, Jääskeläinen T, Lee NR, Lehtimäki T, Lemaitre RN, Lu W, Luben RN, Manichaikul A, Männistö S, Marques-Vidal P, Monda KL, Ngwa JS, Pérusse L, van Rooij FJ, Xiang YB, Wen W, Wojczynski MK, Zhu J, Borecki IB, Bouchard C, Cai Q, Cooper C, Dedoussis GV, Deloukas P, Ferrucci L, Forouhi NG, Hansen T, Christiansen L, Hofman A, Johansson I, Jørgensen T, Karasawa S, Khaw KT, Kim MK, Kristiansson K, Li H, Liu Y, Lohman KK, Long J, Mikkilä V, Mozaffarian D, North K, Pedersen O, Raitakari O, Rissanen H, Tuomilehto J, van der Schouw YT, Uitterlinden AG, Zillikens MC, Franco OH, Shyong Tai E, Ou Shu X, Siscovick DS, Toft U, Verschuren WM, Vollenweider P, Wareham NJ, Witteman JC, Zheng W, Ridker PM, Kang JH, Liang L, Jensen MK, Curhan GC, Pasquale LR, Hunter DJ, Mohlke KL, Uusitupa M, Cupples LA, Rankinen T, Orho-Melander M, Wang T, Chasman DI, Franks PW, Sørensen TI, Hu FB, Loos RJ, Nettleton JA, and Qi L

Human Molecular Genetics. Aug 2014

(DOI : 10.1093/hmg/ddu411)

Opposites don't attract: high spouse concordance for dietary supplement use in the European Prospective Investigation into Cancer in Norfolk (EPIC-Norfolk) cohort study.

Lentjes MA, Welch AA, Keogh RH, Luben RN, and Khaw KT

Public Health Nutrition. Jul 2014

(DOI : 10.1017/S1368980014001396)

Novel Associations between Common Breast Cancer Susceptibility Variants and Risk-Predicting Mammographic Density Measures.

Stone J, Thompson DJ, Dos Santos Silva I, Scott C, Tamimi RM, Lindström S, Kraft P, Hazra A, Li J, Eriksson L, Czene K, Hall P, Jensen M, Cunningham J, Olson JE, Purrington K, Couch FJ, Brown J, Leyland J, Warren RM, Luben RN, Khaw KT, Smith P, Wareham NJ, Jud SM, Heusinger K, Beckmann MW, Douglas JA, Shah KP, Chan HP, Helvie MA, Le Marchand L, Kolonel LN, Woolcott C, Maskarinec G, Haiman C, Giles GG, Baglietto L, Krishnan K, Southey MC, Apicella C, Andrulis IL, Knight JA, Ursin G, Alnaes GI, Kristensen VN, Borresen-Dale AL, Gram IT, Bolla MK, Wang Q, Michailidou K, Dennis J, Simard J, Pharoah P, Dunning AM, Easton DF, Fasching PA, Pankratz VS, Hopper JL, and Vachon CM

Cancer research. Jul 2014

(DOI : 10.1158/0008-5472.CAN-14-2012)

Serum carbon and nitrogen stable isotopes as potential biomarkers of dietary intake and their relation with incident type 2 diabetes: the EPIC-Norfolk study.

Patel PS, Cooper AJ, O'Connell TC, Kuhnle GG, Kneale CK, Mulligan AM, Luben RN, Brage S, Khaw KT, Wareham NJ, and Forouhi NG

The American Journal of Clinical Nutrition. Jul 2014

(DOI : 10.3945/ajcn.113.068577)

Body fat percentage, body mass index and waist-to-hip ratio as predictors of mortality and cardiovascular disease.

Myint PK, Kwok CS, Luben RN, Wareham NJ, and Khaw KT

Heart (British Cardiac Society). Jun 2014

(DOI : 10.1136/heartjnl-2014-305816)

The association between a biomarker score for fruit and vegetable intake and incident type 2 diabetes: the EPIC-Norfolk study.

Cooper AJ, Sharp SJ, Luben RN, Khaw KT, Wareham NJ, and Forouhi NG

European Journal of Clinical Nutrition. Apr 2014

(DOI : 10.1038/ejcn.2014.246)

A new tool for converting food frequency questionnaire data into nutrient and food group values: FETA research methods and availability.

Mulligan AA, Luben RN, Bhaniani A, Parry-Smith DJ, O'Connor L, Khawaja AP, Forouhi NG, and Khaw KT

BMJ Open. Mar 2014

(DOI : 10.1136/bmjopen-2013-004503)

Genome-wide meta-analysis identifies six novel loci associated with habitual coffee consumption.

Cornelis MC, Byrne EM, Esko T, Nalls MA, Ganna A, Paynter N, Monda KL, Amin N, Fischer K, Renstrom F, Ngwa JS, Huikari V, Cavadino A, Nolte IM, Teumer A, Marques-Vidal P, Rawal R, Manichaikul A, Wojczynski MK, Vink JM, Zhao JH, Burlutsky G, Lahti J, Mikkilä V, Lemaitre RN, Eriksson J, Musani SK, Tanaka T, Geller F, Luan J, Mägi R, Dimitriou M, Garcia ME, Wright MJ, Rose LM, Magnusson PK, Pedersen NL, Couper D, Oostra BA, Hofman A, Ikram MA, Tiemeier HW, Uitterlinden AG, van Rooij FJ, Barroso I, Johansson I, Kaakinen M, Milani L, Power C, Snieder H, Stolk RP, Baumeister SE, Biffar R, Bastardot F, Kutalik Z, Jacobs DR, Forouhi NG, Mihailov E, Lind L, Lindgren C, Michaëlsson K, Morris A, Jensen M, Khaw KT, Luben RN, Wang JJ, Männistö S, Perälä MM, Kähönen M, Lehtimäki T, Viikari J, Mozaffarian D, Mukamal K, Psaty BM, Döring A, Heath AC, Montgomery GW, Dahmen N, Carithers T, Tucker KL, Ferrucci L, Boyd HA, Melbye M, Treur JL, Mellström D, Hottenga JJ, Prokopenko I, Tönjes A, Deloukas P, Kanoni S, Lorentzon M, Houston DK, Danesh J, Rasheed A, Mason MA, Zonderman AB, Franke L, Kristal BS, Karjalainen J, Reed DR, Westra HJ, Evans MK, Saleheen D, Harris TB, Dedoussis G, Curhan G, Stumvoll M, Beilby J, Pasquale LR, Feenstra B, Bandinelli S, Ordovas JM, Chan AT, Peters U, Ohlsson C, Gieger C, Martin NG, Waldenberger M, Siscovick DS, Raitakari O, Eriksson JG, Mitchell P, Hunter DJ, Kraft P, Rimm EB, Boomsma DI, Borecki IB, Loos RJ, Wareham NJ, Vollenweider P, Caporaso N, Grabe HJ, Neuhouser ML, Wolffenbuttel BH, Hyppönen E, Järvelin MR, Cupples LA, Franks PW, Ridker PM, van Duijn CM, Heiss G, Metspalu A, North KE, Ingelsson E, Nettleton JA, van Dam RM, and Chasman DI

Molecular psychiatry. Mar 2014

(DOI : 10.1038/mp.2014.107)

Bone mineral density and incidence of stroke: European prospective investigation into cancer-norfolk population-based study, systematic review, and meta-analysis.

Myint PK, Clark AB, Kwok CS, Loke YK, Yeong JK, Luben RN, Wareham NJ, and Khaw KT

Stroke. Jan 2014

(DOI : 10.1161/STROKEAHA.113.002999)

Assessment of the dietary intake of total flavan-3-ols, monomeric flavan-3-ols, proanthocyanidins and theaflavins in the European Union.

Vogiatzoglou A, Mulligan AA, Luben RN, Lentjes MA, Heiss C, Kelm M, Merx MW, Spencer JP, Schroeter H, and Kuhnle GG

The British journal of nutrition. Dec 2013

(DOI : 10.1017/S0007114513003930)

Longitudinal association of C-reactive protein and lung function over 13 years: The EPIC-Norfolk study.

Ahmadi-Abhari S, Kaptoge S, Luben RN, Wareham NJ, and Khaw KT

American Journal of Epidemiology. Sep 2013

(DOI : 10.1093/aje/kwt208)

Dietary dairy product intake and incident type 2 diabetes: a prospective study using dietary data from a 7-day food diary.

O'Connor L, Lentjes MA, Luben RN, Khaw KT, Wareham NJ, and Forouhi NG

Diabetologia. Sep 2013

(DOI : 10.1007/s00125-014-3176-1)

Dietary intake measurement using 7 d diet diaries in British men and women in the European Prospective Investigation into Cancer-Norfolk study: a focus on methodological issues.

Lentjes MA, McTaggart A, Mulligan AA, Powell NA, Parry-Smith D, Luben RN, Bhaniani A, Welch AA, and Khaw KT

The British journal of nutrition. Sep 2013

(DOI : 10.1017/S0007114513002754)

Dietary intake of carbohydrates and risk of type 2 diabetes: the European Prospective Investigation into Cancer-Norfolk study.

Ahmadi-Abhari S, Luben RN, Powell N, Bhaniani A, Chowdhury R, Wareham NJ, Forouhi NG, and Khaw KT

The British journal of nutrition. Jul 2013

(DOI : 10.1017/S0007114513002298)

Differences in dietary supplement use and secular and seasonal trends assessed using three different instruments in the EPIC-Norfolk population study.

Lentjes MA, Welch AA, Luben RN, and Khaw KT

Journal of dietary supplements. Jun 2013

(DOI : 10.3109/19390211.2013.790336)

Social adversity experience and blood pressure control following antihypertensive medication use in a community sample of older adults.

Wainwright NW, Levy S, Pico J, Luben RN, Surtees PG, and Khaw KT

International journal of behavioral medicine. May 2013

(DOI : 10.1007/s12529-013-9319-9)

Estimated dietary intakes and sources of flavanols in the German population (German National Nutrition Survey II).

Vogiatzoglou A, Heuer T, Mulligan AA, Lentjes MA, Luben RN, and Kuhnle GG

European journal of nutrition. Apr 2013

(DOI : 10.1007/s00394-013-0572-0)

Using lifestyle factors to identify individuals at higher risk of inflammatory polyarthritis (results from the European Prospective Investigation of Cancer-Norfolk and the Norfolk Arthritis Register--the EPIC-2-NOAR Study).

Lahiri M, Luben RN, Morgan C, Bunn DK, Marshall T, Lunt M, Verstappen SM, Symmons DP, Khaw KT, Wareham N, and Bruce IN

Annals of the rheumatic diseases. Mar 2013

(DOI : 10.1136/annrheumdis-2012-202481)

Common genetic variants of the natriuretic peptide gene locus are not associated with heart failure risk in participants in the EPIC-Norfolk study.

Pfister R, Luben RN, Khaw KT, and Wareham NJ

European journal of heart failure. Jan 2013

(DOI : 10.1093/eurjhf/hft007)

Seventeen year risk of all-cause and cause-specific mortality associated with C-reactive protein, fibrinogen and leukocyte count in men and women: the EPIC-Norfolk study.

Ahmadi-Abhari S, Luben RN, Wareham NJ, and Khaw KT

European Journal of Epidemiology. Jan 2013

(DOI : 10.1007/s10654-013-9819-6)

Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders.

den Hoed M, Eijgelsheim M, Esko T, Brundel BJ, Peal DS, Evans DM, Nolte IM, Segrè AV, Holm H, Handsaker RE, Westra HJ, Johnson T, Isaacs A, Yang J, Lundby A, Zhao JH, Kim YJ, Go MJ, Almgren P, Bochud M, Boucher G, Cornelis MC, Gudbjartsson D, Hadley D, van der Harst P, Hayward C, den Heijer M, Igl W, Jackson AU, Kutalik Z, Luan J, Kemp JP, Kristiansson K, Ladenvall C, Lorentzon M, Montasser ME, Njajou OT, O'Reilly PF, Padmanabhan S, St Pourcain B, Rankinen T, Salo P, Tanaka T, Timpson NJ, Vitart V, Waite L, Wheeler W, Zhang W, Draisma HH, Feitosa MF, Kerr KF, Lind PA, Mihailov E, Onland-Moret NC, Song C, Weedon MN, Xie W, Yengo L, Absher D, Albert CM, Alonso A, Arking DE, de Bakker PI, Balkau B, Barlassina C, Benaglio P, Bis JC, Bouatia-Naji N, Brage S, Chanock SJ, Chines PS, Chung M, Darbar D, Dina C, Dörr M, Elliott P, Felix SB, Fischer K, Fuchsberger C, de Geus EJ, Goyette P, Gudnason V, Harris TB, Hartikainen AL, Havulinna AS, Heckbert SR, Hicks AA, Hofman A, Holewijn S, Hoogstra-Berends F, Hottenga JJ, Jensen MK, Johansson Å, Junttila J, Kääb S, Kanon B, Ketkar S, Khaw KT, Knowles JW, Kooner AS, Kors JA, Kumari M, Milani L, Laiho P, Lakatta EG, Langenberg C, Leusink M, Liu Y, Luben RN, Lunetta KL, Lynch SN, Markus MR, Marques-Vidal P, Mateo Leach I, McArdle WL, McCarroll SA, Medland SE, Miller KA, Montgomery GW, Morrison AC, Müller-Nurasyid M, Navarro P, Nelis M, O'Connell JR, O'Donnell CJ, Ong KK, Newman AB, Peters A, Polasek O, Pouta A, Pramstaller PP, Psaty BM, Rao DC, Ring SM, Rossin EJ, Rudan D, Sanna S, Scott RA, Sehmi JS, Sharp SJ, Shin JT, Singleton AB, Smith AV, Soranzo N, Spector TD, Stewart C, Stringham HM, Tarasov KV, Uitterlinden AG, Vandenput L, Hwang SJ, Whitfield JB, Wijmenga C, Wild SH, Willemsen G, Wilson JF, Witteman JC, Wong A, Wong Q, Jamshidi Y, Zitting P, Boer JM, Boomsma DI, Borecki IB, van Duijn CM, Ekelund U, Forouhi NG, Froguel P, Hingorani A, Ingelsson E, Kivimaki M, Kronmal RA, Kuh D, Lind L, Martin NG, Oostra BA, Pedersen NL, Quertermous T, Rotter JI, van der Schouw YT, Verschuren WM, Walker M, Albanes D, Arnar DO, Assimes TL, Bandinelli S, Boehnke M, de Boer RA, Bouchard C, Caulfield WL, Chambers JC, Curhan G, Cusi D, Eriksson J, Ferrucci L, van Gilst WH, Glorioso N, de Graaf J, Groop L, Gyllensten U, Hsueh WC, Hu FB, Huikuri HV, Hunter DJ, Iribarren C, Isomaa B, Järvelin MR, Jula A, Kähönen M, Kiemeney LA, van der Klauw MM, Kooner JS, Kraft P, Iacoviello L, Lehtimäki T, Lokki ML, Mitchell BD, Navis G, Nieminen MS, Ohlsson C, Poulter NR, Qi L, Raitakari OT, Rimm EB, Rioux JD, Rizzi F, Rudan I, Salomaa V, Sever PS, Shields DC, Shuldiner AR, Sinisalo J, Stanton AV, Stolk RP, Strachan DP, Tardif JC, Thorsteinsdottir U, Tuomilehto J, van Veldhuisen DJ, Virtamo J, Viikari J, Vollenweider P, Waeber G, Widén E, Cho YS, Olsen JV, Visscher PM, Willer C, Franke L, Erdmann J, Thompson JR, Pfeufer A, Sotoodehnia N, Newton-Cheh C, Ellinor PT, Stricker BH, Metspalu A, Perola M, Beckmann JS, Smith GD, Stefansson K, Wareham NJ, Munroe PB, Sibon OC, Milan DJ, Snieder H, Samani NJ, and Loos RJ

Nature genetics. Dec 2012

(DOI : 10.1038/ng.2610)

C-reactive protein and fracture risk: European prospective investigation into Cancer Norfolk Study.

Ahmadi-Abhari S, Luben RN, Wareham NJ, and Khaw KT

Bone. Nov 2012

(DOI : 10.1016/j.bone.2013.05.009)

Distribution and determinants of C-reactive protein in the older adult population: European Prospective Investigation into Cancer-Norfolk study.

Ahmadi-Abhari S, Luben RN, Wareham NJ, and Khaw KT

European journal of clinical investigation. Nov 2012

(DOI : 10.1111/eci.12116)

Lipoprotein(a) and risk of coronary, cerebrovascular, and peripheral artery disease: the EPIC-Norfolk prospective population study.

Gurdasani D, Sjouke B, Tsimikas S, Hovingh GK, Luben RN, Wainwright NW, Pomilla C, Wareham NJ, Khaw KT, Boekholdt SM, and Sandhu MS

Arteriosclerosis, thrombosis, and vascular biology. Oct 2012

(DOI : 10.1161/ATVBAHA.112.255521)

Demographic and disease-related predictors of abnormal lung function in patients with established inflammatory polyarthritis and a comparison with the general population.

Verstappen SM, Lunt M, Luben RN, Chipping J, Marshall T, Khaw KT, Wareham NJ, Dixon WG, Bruce IN, and Symmons DP

Annals of the rheumatic diseases. Oct 2012

(DOI : 10.1136/annrheumdis-2012-201698)

Identification of a novel percent mammographic density locus at 12q24.

Stevens KN, Lindström S, Scott CG, Thompson D, Sellers TA, Wang X, Wang A, Atkinson E, Rider DN, Eckel-Passow JE, Varghese JS, Audley T, Brown J, Leyland J, Luben RN, Warren RM, Loos RJ, Wareham NJ, Li J, Hall P, Liu J, Eriksson L, Czene K, Olson JE, Pankratz VS, Fredericksen Z, Diasio RB, Lee AM, Heit JA, DeAndrade M, Goode EL, Vierkant RA, Cunningham JM, Armasu SM, Weinshilboum R, Fridley BL, Batzler A, Ingle JN, Boyd NF, Paterson AD, Rommens J, Martin LJ, Hopper JL, Southey MC, Stone J, Apicella C, Kraft P, Hankinson SE, Hazra A, Hunter DJ, Easton DF, Couch FJ, Tamimi RM, and Vachon CM

Human Molecular Genetics. Apr 2012

(DOI : 10.1093/hmg/dds158)

Subclinical hyperthyroidism and the risk of coronary heart disease and mortality.

Collet TH, Gussekloo J, Bauer DC, den Elzen WP, Cappola AR, Balmer P, Iervasi G, Åsvold BO, Sgarbi JA, Völzke H, Gencer B, Maciel RM, Molinaro S, Bremner A, Luben RN, Maisonneuve P, Cornuz J, Newman AB, Khaw KT, Westendorp RG, Franklyn JA, Vittinghoff E, Walsh JP, Rodondi N, and Thyroid Studies Collaboration Thyroid Studies Collaboration

Archives of internal medicine. Apr 2012

(DOI : 10.1001/archinternmed.2012.402)

A prospective study of the association between quantity and variety of fruit and vegetable intake and incident type 2 diabetes.

Cooper AJ, Sharp SJ, Lentjes MA, Luben RN, Khaw KT, Wareham NJ, and Forouhi NG

Diabetes care. Apr 2012

(DOI : 10.2337/dc11-2388)

Common breast cancer susceptibility variants in LSP1 and RAD51L1 are associated with mammographic density measures that predict breast cancer risk.

Vachon CM, Scott CG, Fasching PA, Hall P, Tamimi RM, Li J, Stone J, Apicella C, Odefrey F, Gierach GL, Jud SM, Heusinger K, Beckmann MW, Pollan M, Fernández-Navarro P, González-Neira A, Benitez J, van Gils CH, Lokate M, Onland-Moret NC, Peeters PH, Brown J, Leyland J, Varghese JS, Easton DF, Thompson DJ, Luben RN, Warren RM, Wareham NJ, Loos RJ, Khaw KT, Ursin G, Lee E, Gayther SA, Ramus SJ, Eeles RA, Leach MO, Kwan-Lim G, Couch FJ, Giles GG, Baglietto L, Krishnan K, Southey MC, Le Marchand L, Kolonel LN, Woolcott C, Maskarinec G, Haiman CA, Walker K, Johnson N, McCormack VA, Biong M, Alnaes GI, Gram IT, Kristensen VN, Børresen-Dale AL, Lindström S, Hankinson SE, Hunter DJ, Andrulis IL, Knight JA, Boyd NF, Figuero JD, Lissowska J, Wesolowska E, Peplonska B, Bukowska A, Reszka E, Liu J, Eriksson L, Czene K, Audley T, Wu AH, Pankratz VS, Hopper JL, and Dos-Santos-Silva I

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. Mar 2012

(DOI : 10.1158/1055-9965.EPI-12-0066)

Mammographic breast density and breast cancer: evidence of a shared genetic basis.

Varghese JS, Thompson DJ, Michailidou K, Lindström S, Turnbull C, Brown J, Leyland J, Warren RM, Luben RN, Loos RJ, Wareham NJ, Rommens J, Paterson AD, Martin LJ, Vachon CM, Scott CG, Atkinson EJ, Couch FJ, Apicella C, Southey MC, Stone J, Li J, Eriksson L, Czene K, Boyd NF, Hall P, Hopper JL, Tamimi RM, Rahman N, and Easton DF

Cancer research. Jan 2012

(DOI : 10.1158/0008-5472.CAN-11-3295)

Fibre intake in relation to serum total cholesterol levels and CHD risk: a comparison of dietary assessment methods.

Ward HA, Keogh R, Lentjes M, Luben RN, Wareham NJ, and Khaw KT

European Journal of Clinical Nutrition. Nov 2011

(DOI : 10.1038/ejcn.2011.184)

Testosterone, SHBG and differential white blood cell count in middle-aged and older men.

Brand JS, van der Schouw YT, Dowsett M, Folkerd E, Luben RN, Wareham NJ, and Khaw KT

Maturitas. Oct 2011

(DOI : 10.1016/j.maturitas.2011.12.007)

Educational attainment and mean leukocyte telomere length in women in the European Prospective Investigation into Cancer (EPIC)-Norfolk population study.

Surtees PG, Wainwright NW, Pooley KA, Luben RN, Khaw KT, Easton DF, and Dunning AM

Brain, behavior, and immunity. Sep 2011

(DOI : 10.1016/j.bbi.2011.11.009)

A latent variable partial least squares path modeling approach to regional association and polygenic effect with applications to a human obesity study.

Xue F, Li S, Luan J, Yuan Z, Luben RN, Khaw KT, Wareham NJ, Loos RJ, and Zhao JH

PLoS ONE. Aug 2011

(DOI : 10.1371/journal.pone.0031927)

Body fat mass is a predictor of risk of osteoporotic fractures in women but not in men: a prospective population study.

Moayyeri A, Luben RN, Wareham NJ, and Khaw KT

Journal of internal medicine. Aug 2011

(DOI : 10.1111/j.1365-2796.2011.02443.x)

Cigarette smoking and endogenous sex hormones in postmenopausal women.

Brand JS, Chan MF, Dowsett M, Folkerd E, Wareham NJ, Luben RN, van der Schouw YT, and Khaw KT

The Journal of clinical endocrinology and metabolism. Aug 2011

(DOI : 10.1210/jc.2011-1165)

Life stress, emotional health, and mean telomere length in the European Prospective Investigation into Cancer (EPIC)-Norfolk population study.

Surtees PG, Wainwright NW, Pooley KA, Luben RN, Khaw KT, Easton DF, and Dunning AM

The journals of gerontology. Series A, Biological sciences and medical sciences. Jul 2011

(DOI : 10.1093/gerona/glr112)

Association between plasma vitamin C concentrations and blood pressure in the European prospective investigation into cancer-Norfolk population-based study.

Myint PK, Luben RN, Wareham NJ, and Khaw KT

Hypertension (Dallas, Tex. : 1979). Jul 2011

(DOI : 10.1161/HYPERTENSIONAHA.111.171108)

Association between dietary phyto-oestrogens and bone density in men and postmenopausal women.

Kuhnle GG, Ward HA, Vogiatzoglou A, Luben RN, Mulligan A, Wareham NJ, Forouhi NG, and Khaw KT

The British journal of nutrition. Jul 2011

(DOI : 10.1017/S0007114511001309)

The aetiology of symptomatic gallstones quantification of the effects of obesity, alcohol and serum lipids on risk. Epidemiological and biomarker data from a UK prospective cohort study (EPIC-Norfolk).

Banim PJ, Luben RN, Bulluck H, Sharp SJ, Wareham NJ, Khaw KT, and Hart AR

European journal of gastroenterology & hepatology. May 2011

(DOI : 10.1097/MEG.0b013e3283477cc9)

Lifestyle behaviours and quality-adjusted life years in middle and older age.

Myint PK, Smith RD, Luben RN, Surtees PG, Wainwright NW, Wareham NJ, and Khaw KT

Age and ageing. May 2011

(DOI : 10.1093/ageing/afr058)

N-Nitroso compounds and cancer incidence: the European Prospective Investigation into Cancer and Nutrition (EPIC)-Norfolk Study.

Loh YH, Jakszyn P, Luben RN, Mulligan AA, Mitrou PN, and Khaw KT

The American Journal of Clinical Nutrition. Mar 2011

(DOI : 10.3945/ajcn.111.012377)

Self-reported and measured anthropometric data and risk of colorectal cancer in the EPIC-Norfolk study.

Park JY, Mitrou PN, Keogh RH, Luben RN, Wareham NJ, and Khaw KT

International Journal of Obesity. Mar 2011

(DOI : 10.1038/ijo.2011.61)

Individual and cumulative effect of type 2 diabetes genetic susceptibility variants on risk of coronary heart disease.

Pfister R, Barnes D, Luben RN, Khaw KT, Wareham NJ, and Langenberg C

Diabetologia. Jan 2011

(DOI : 10.1007/s00125-011-2206-5)

Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile.

Kilpeläinen TO, Zillikens MC, Stančáková A, Finucane FM, Ried JS, Langenberg C, Zhang W, Beckmann JS, Luan J, Vandenput L, Styrkarsdottir U, Zhou Y, Smith AV, Zhao JH, Amin N, Vedantam S, Shin SY, Haritunians T, Fu M, Feitosa MF, Kumari M, Halldorsson BV, Tikkanen E, Mangino M, Hayward C, Song C, Arnold AM, Aulchenko YS, Oostra BA, Campbell H, Cupples LA, Davis KE, Döring A, Eiriksdottir G, Estrada K, Fernández-Real JM, Garcia M, Gieger C, Glazer NL, Guiducci C, Hofman A, Humphries SE, Isomaa B, Jacobs LC, Jula A, Karasik D, Karlsson MK, Khaw KT, Kim LJ, Kivimaki M, Klopp N, Kühnel B, Kuusisto J, Liu Y, Ljunggren Ö, Lorentzon M, Luben RN, McKnight B, Mellström D, Mitchell BD, Mooser V, Moreno JM, Männistö S, O'Connell JR, Pascoe L, Peltonen L, Peral B, Perola M, Psaty BM, Salomaa V, Savage DB, Semple RK, Skaric-Juric T, Sigurdsson G, Song KS, Spector TD, Syvänen AC, Talmud PJ, Thorleifsson G, Thorsteinsdottir U, Uitterlinden AG, van Duijn CM, Vidal-Puig A, Wild SH, Wright AF, Clegg DJ, Schadt E, Wilson JF, Rudan I, Ripatti S, Borecki IB, Shuldiner AR, Ingelsson E, Jansson JO, Kaplan RC, Gudnason V, Harris TB, Groop L, Kiel DP, Rivadeneira F, Walker M, Barroso I, Vollenweider P, Waeber G, Chambers JC, Kooner JS, Soranzo N, Hirschhorn JN, Stefansson K, Wichmann HE, Ohlsson C, O'Rahilly S, Wareham NJ, Speliotes EK, Fox CS, Laakso M, and Loos RJ

Nature genetics. Jan 2011

(DOI : 10.1038/ng.866)

Effects of body size and sociodemographic characteristics on differences between self-reported and measured anthropometric data in middle-aged men and women: the EPIC-Norfolk study.

Park JY, Mitrou PN, Keogh RH, Luben RN, Wareham NJ, and Khaw KT

European Journal of Clinical Nutrition. Dec 2010

(DOI : 10.1038/ejcn.2010.259)

Associations of endogenous testosterone and SHBG with glycated haemoglobin in middle-aged and older men.

Brand JS, Wareham NJ, Dowsett M, Folkerd E, van der Schouw YT, Luben RN, and Khaw KT

Clinical endocrinology. Dec 2010

(DOI : 10.1111/j.1365-2265.2010.03951.x)

Mendelian Randomisation Study of Childhood BMI and Early Menarche.

Mumby HS, Elks CE, Li S, Sharp SJ, Khaw KT, Luben RN, Wareham NJ, Loos RJ, and Ong KK

Journal of Obesity. Dec 2010

(DOI : 10.1155/2011/180729)

Alterations in PTEN and PIK3CA in colorectal cancers in the EPIC Norfolk study: associations with clinicopathological and dietary factors.

Naguib A, Cooke JC, Happerfield L, Kerr L, Gay LJ, Luben RN, Ball RY, Mitrou PN, McTaggart A, and Arends MJ

BMC cancer. Nov 2010

(DOI : 10.1186/1471-2407-11-123)

Fatty acids measured in plasma and erythrocyte-membrane phospholipids and derived by food-frequency questionnaire and the risk of new-onset type 2 diabetes: a pilot study in the European Prospective Investigation into Cancer and Nutrition (EPIC)-Norfolk cohort.

Patel PS, Sharp SJ, Jansen E, Luben RN, Khaw KT, Wareham NJ, and Forouhi NG

The American Journal of Clinical Nutrition. Sep 2010

(DOI : 10.3945/ajcn.2010.29182)

CHD risk in relation to alcohol intake from categorical and open-ended dietary instruments.

Ward H, Luben RN, Wareham NJ, and Khaw KT

Public Health Nutrition. Aug 2010

(DOI : 10.1017/S1368980010002041)

Alcohol intake and risk of colorectal cancer: results from the UK Dietary Cohort Consortium.

Park JY, Dahm CC, Keogh RH, Mitrou PN, Cairns BJ, Greenwood DC, Spencer EA, Fentiman IS, Shipley MJ, Brunner EJ, Cade JE, Burley VJ, Mishra GD, Kuh D, Stephen AM, White IR, Luben RN, Mulligan AA, Khaw KT, and Rodwell SA

British journal of cancer. Jul 2010

(DOI : 10.1038/sj.bjc.6605802)

Genetic predisposition to obesity leads to increased risk of type 2 diabetes.

Li S, Zhao JH, Luan J, Langenberg C, Luben RN, Khaw KT, Wareham NJ, and Loos RJ

Diabetologia. Jul 2010

(DOI : 10.1007/s00125-011-2044-5)

Incidence of type 2 diabetes using proposed HbA1c diagnostic criteria in the european prospective investigation of cancer-norfolk cohort: implications for preventive strategies.

Chamnan P, Simmons RK, Forouhi NG, Luben RN, Khaw KT, Wareham NJ, and Griffin SJ

Diabetes care. Jul 2010

(DOI : 10.2337/dc09-2326)

Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index.

Speliotes EK, Willer CJ, Berndt SI, Monda KL, Thorleifsson G, Jackson AU, Lango Allen H, Lindgren CM, Luan J, Mägi R, Randall JC, Vedantam S, Winkler TW, Qi L, Workalemahu T, Heid IM, Steinthorsdottir V, Stringham HM, Weedon MN, Wheeler E, Wood AR, Ferreira T, Weyant RJ, Segrè AV, Estrada K, Liang L, Nemesh J, Park JH, Gustafsson S, Kilpeläinen TO, Yang J, Bouatia-Naji N, Esko T, Feitosa MF, Kutalik Z, Mangino M, Raychaudhuri S, Scherag A, Smith AV, Welch R, Zhao JH, Aben KK, Absher DM, Amin N, Dixon AL, Fisher E, Glazer NL, Goddard ME, Heard-Costa NL, Hoesel V, Hottenga JJ, Johansson Å, Johnson T, Ketkar S, Lamina C, Li S, Moffatt MF, Myers RH, Narisu N, Perry JR, Peters MJ, Preuss M, Ripatti S, Rivadeneira F, Sandholt C, Scott LJ, Timpson NJ, Tyrer JP, van Wingerden S, Watanabe RM, White CC, Wiklund F, Barlassina C, Chasman DI, Cooper MN, Jansson JO, Lawrence RW, Pellikka N, Prokopenko I, Shi J, Thiering E, Alavere H, Alibrandi MT, Almgren P, Arnold AM, Aspelund T, Atwood LD, Balkau B, Balmforth AJ, Bennett AJ, Ben-Shlomo Y, Bergman RN, Bergmann S, Biebermann H, Blakemore AI, Boes T, Bonnycastle LL, Bornstein SR, Brown MJ, Buchanan TA, Busonero F, Campbell H, Cappuccio FP, Cavalcanti-Proença C, Chen YD, Chen CM, Chines PS, Clarke R, Coin L, Connell J, Day IN, den Heijer M, Duan J, Ebrahim S, Elliott P, Elosua R, Eiriksdottir G, Erdos MR, Eriksson JG, Facheris MF, Felix SB, Fischer-Posovszky P, Folsom AR, Friedrich N, Freimer NB, Fu M, Gaget S, Gejman PV, Geus EJ, Gieger C, Gjesing AP, Goel A, Goyette P, Grallert H, Gräßler J, Greenawalt DM, Groves CJ, Gudnason V, Guiducci C, Hartikainen AL, Hassanali N, Hall AS, Havulinna AS, Hayward C, Heath AC, Hengstenberg C, Hicks AA, Hinney A, Hofman A, Homuth G, Hui J, Igl W, Iribarren C, Isomaa B, Jacobs KB, Jarick I, Jewell E, John U, Jørgensen T, Jousilahti P, Jula A, Kaakinen M, Kajantie E, Kaplan LM, Kathiresan S, Kettunen J, Kinnunen L, Knowles JW, Kolcic I, König IR, Koskinen S, Kovacs P, Kuusisto J, Kraft P, Kvaløy K, Laitinen J, Lantieri O, Lanzani C, Launer LJ, Lecoeur C, Lehtimäki T, Lettre G, Liu J, Lokki ML, Lorentzon M, Luben RN, Ludwig B, Manunta P, Marek D, Marre M, Martin NG, McArdle WL, McCarthy A, McKnight B, Meitinger T, Melander O, Meyre D, Midthjell K, Montgomery GW, Morken MA, Morris AP, Mulic R, Ngwa JS, Nelis M, Neville MJ, Nyholt DR, O'Donnell CJ, O'Rahilly S, Ong KK, Oostra B, Pare G, Parker AN, Perola M, Pichler I, Pietiläinen KH, Platou CG, Polasek O, Pouta A, Rafelt S, Raitakari O, Rayner NW, Ridderstråle M, Rief W, Ruokonen A, Robertson NR, Rzehak P, Salomaa V, Sanders AR, Sandhu MS, Sanna S, Saramies J, Savolainen MJ, Scherag S, Schipf S, Schreiber S, Schunkert H, Silander K, Sinisalo J, Siscovick DS, Smit JH, Soranzo N, Sovio U, Stephens J, Surakka I, Swift AJ, Tammesoo ML, Tardif JC, Teder-Laving M, Teslovich TM, Thompson JR, Thomson B, Tönjes A, Tuomi T, van Meurs JB, van Ommen GJ, Vatin V, Viikari J, Visvikis-Siest S, Vitart V, Vogel CI, Voight BF, Waite LL, Wallaschofski H, Walters GB, Widén E, Wiegand S, Wild SH, Willemsen G, Witte DR, Witteman JC, Xu J, Zhang Q, Zgaga L, Ziegler A, Zitting P, Beilby JP, Farooqi IS, Hebebrand J, Huikuri HV, James AL, Kähönen M, Levinson DF, Macciardi F, Nieminen MS, Ohlsson C, Palmer LJ, Ridker PM, Stumvoll M, Beckmann JS, Boeing H, Boerwinkle E, Boomsma DI, Caulfield MJ, Chanock SJ, Collins FS, Cupples LA, Smith GD, Erdmann J, Froguel P, Grönberg H, Gyllensten U, Hall P, Hansen T, Harris TB, Hattersley AT, Hayes RB, Heinrich J, Hu FB, Hveem K, Illig T, Järvelin MR, Kaprio J, Karpe F, Khaw KT, Kiemeney LA, Krude H, Laakso M, Lawlor DA, Metspalu A, Munroe PB, Ouwehand WH, Pedersen O, Penninx BW, Peters A, Pramstaller PP, Quertermous T, Reinehr T, Rissanen A, Rudan I, Samani NJ, Schwarz PE, Shuldiner AR, Spector TD, Tuomilehto J, Uda M, Uitterlinden A, Valle TT, Wabitsch M, Waeber G, Wareham NJ, Watkins H, Wilson JF, Wright AF, Zillikens MC, Chatterjee N, McCarroll SA, Purcell S, Schadt EE, Visscher PM, Assimes TL, Borecki IB, Deloukas P, Fox CS, Groop LC, Haritunians T, Hunter DJ, Kaplan RC, Mohlke KL, O'Connell JR, Peltonen L, Schlessinger D, Strachan DP, van Duijn CM, Wichmann HE, Frayling TM, Thorsteinsdottir U, Abecasis GR, Barroso I, Boehnke M, Stefansson K, North KE, McCarthy MI, Hirschhorn JN, Ingelsson E, and Loos RJ

Nature genetics. May 2010

(DOI : 10.1038/ng.686)

Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution.

Heid IM, Jackson AU, Randall JC, Winkler TW, Qi L, Steinthorsdottir V, Thorleifsson G, Zillikens MC, Speliotes EK, Mägi R, Workalemahu T, White CC, Bouatia-Naji N, Harris TB, Berndt SI, Ingelsson E, Willer CJ, Weedon MN, Luan J, Vedantam S, Esko T, Kilpeläinen TO, Kutalik Z, Li S, Monda KL, Dixon AL, Holmes CC, Kaplan LM, Liang L, Min JL, Moffatt MF, Molony C, Nicholson G, Schadt EE, Zondervan KT, Feitosa MF, Ferreira T, Lango Allen H, Weyant RJ, Wheeler E, Wood AR, Estrada K, Goddard ME, Lettre G, Mangino M, Nyholt DR, Purcell S, Smith AV, Visscher PM, Yang J, McCarroll SA, Nemesh J, Voight BF, Absher D, Amin N, Aspelund T, Coin L, Glazer NL, Hayward C, Heard-Costa NL, Hottenga JJ, Johansson Å, Johnson T, Kaakinen M, Kapur K, Ketkar S, Knowles JW, Kraft P, Kraja AT, Lamina C, Leitzmann MF, McKnight B, Morris AP, Ong KK, Perry JR, Peters MJ, Polasek O, Prokopenko I, Rayner NW, Ripatti S, Rivadeneira F, Robertson NR, Sanna S, Sovio U, Surakka I, Teumer A, van Wingerden S, Vitart V, Zhao JH, Cavalcanti-Proença C, Chines PS, Fisher E, Kulzer JR, Lecoeur C, Narisu N, Sandholt C, Scott LJ, Silander K, Stark K, Tammesoo ML, Teslovich TM, Timpson NJ, Watanabe RM, Welch R, Chasman DI, Cooper MN, Jansson JO, Kettunen J, Lawrence RW, Pellikka N, Perola M, Vandenput L, Alavere H, Almgren P, Atwood LD, Bennett AJ, Biffar R, Bonnycastle LL, Bornstein SR, Buchanan TA, Campbell H, Day IN, Dei M, Dörr M, Elliott P, Erdos MR, Eriksson JG, Freimer NB, Fu M, Gaget S, Geus EJ, Gjesing AP, Grallert H, Gräßler J, Groves CJ, Guiducci C, Hartikainen AL, Hassanali N, Havulinna AS, Herzig KH, Hicks AA, Hui J, Igl W, Jousilahti P, Jula A, Kajantie E, Kinnunen L, Kolcic I, Koskinen S, Kovacs P, Kroemer HK, Krzelj V, Kuusisto J, Kvaloy K, Laitinen J, Lantieri O, Lathrop GM, Lokki ML, Luben RN, Ludwig B, McArdle WL, McCarthy A, Morken MA, Nelis M, Neville MJ, Pare G, Parker AN, Peden JF, Pichler I, Pietiläinen KH, Platou CG, Pouta A, Ridderstråle M, Samani NJ, Saramies J, Sinisalo J, Smit JH, Strawbridge RJ, Stringham HM, Swift AJ, Teder-Laving M, Thomson B, Usala G, van Meurs JB, van Ommen GJ, Vatin V, Volpato CB, Wallaschofski H, Walters GB, Widén E, Wild SH, Willemsen G, Witte DR, Zgaga L, Zitting P, Beilby JP, James AL, Kähönen M, Lehtimäki T, Nieminen MS, Ohlsson C, Palmer LJ, Raitakari O, Ridker PM, Stumvoll M, Tönjes A, Viikari J, Balkau B, Ben-Shlomo Y, Bergman RN, Boeing H, Smith GD, Ebrahim S, Froguel P, Hansen T, Hengstenberg C, Hveem K, Isomaa B, Jørgensen T, Karpe F, Khaw KT, Laakso M, Lawlor DA, Marre M, Meitinger T, Metspalu A, Midthjell K, Pedersen O, Salomaa V, Schwarz PE, Tuomi T, Tuomilehto J, Valle TT, Wareham NJ, Arnold AM, Beckmann JS, Bergmann S, Boerwinkle E, Boomsma DI, Caulfield MJ, Collins FS, Eiriksdottir G, Gudnason V, Gyllensten U, Hamsten A, Hattersley AT, Hofman A, Hu FB, Illig T, Iribarren C, Järvelin MR, Kao WH, Kaprio J, Launer LJ, Munroe PB, Oostra B, Penninx BW, Pramstaller PP, Psaty BM, Quertermous T, Rissanen A, Rudan I, Shuldiner AR, Soranzo N, Spector TD, Syvänen AC, Uda M, Uitterlinden A, Völzke H, Vollenweider P, Wilson JF, Witteman JC, Wright AF, Abecasis GR, Boehnke M, Borecki IB, Deloukas P, Frayling TM, Groop LC, Haritunians T, Hunter DJ, Kaplan RC, North KE, O'Connell JR, Peltonen L, Schlessinger D, Strachan DP, Hirschhorn JN, Assimes TL, Wichmann HE, Thorsteinsdottir U, van Duijn CM, Stefansson K, Cupples LA, Loos RJ, Barroso I, McCarthy MI, Fox CS, Mohlke KL, and Lindgren CM

Nature genetics. May 2010

(DOI : 10.1038/ng.685)

Physical functional health predicts the incidence of coronary heart disease in the European Prospective Investigation into Cancer-Norfolk prospective population-based study.

Myint PK, Luben RN, Surtees PG, Wainwright NW, Wareham NJ, and Khaw KT

International Journal of Epidemiology. Apr 2010

(DOI : 10.1093/ije/dyq061)

SMAD7 and MGMT genotype variants and cancer incidence in the European Prospective Investigation into Cancer and Nutrition (EPIC)-Norfolk Study.

Loh YH, Mitrou PN, Wood A, Luben RN, McTaggart A, Khaw KT, and Rodwell SA

Cancer Epidemiology. Apr 2010

(DOI : 10.1016/j.canep.2010.09.011)

Telomere length in prospective and retrospective cancer case-control studies.

Pooley KA, Sandhu MS, Tyrer J, Shah M, Driver KE, Luben RN, Bingham SA, Ponder BA, Pharoah PD, Khaw KT, Easton DF, and Dunning AM

Cancer research. Apr 2010

(DOI : PMC2855947)

The association between physical activity in different domains of life and risk of osteoporotic fractures.

Moayyeri A, Besson H, Luben RN, Wareham NJ, and Khaw KT

Bone. Mar 2010

(DOI : 10.1016/j.bone.2010.06.023)

Lifestyle factors and p53 mutation patterns in colorectal cancer patients in the EPIC-Norfolk study.

Park JY, Mitrou PN, Keen J, Dahm CC, Gay LJ, Luben RN, McTaggart A, Khaw KT, Ball RY, Arends MJ, and Rodwell SA

Mutagenesis. Mar 2010

(DOI : 10.1093/mutage/geq012)

Physical activity attenuates the genetic predisposition to obesity in 20,000 men and women from EPIC-Norfolk prospective population study.

Li S, Zhao JH, Luan J, Ekelund U, Luben RN, Khaw KT, Wareham NJ, and Loos RJ

PLoS Medicine. Feb 2010

(DOI : 10.1371/journal.pmed.1000332)

Physical activity reduces the risk of symptomatic gallstones: a prospective cohort study.

Banim PJ, Luben RN, Wareham NJ, Sharp SJ, Khaw KT, and Hart AR

European journal of gastroenterology & hepatology. Feb 2010

(DOI : 10.1097/MEG.0b013e32833732c3)

Breast, colorectal, and prostate cancer risk in the European Prospective Investigation into Cancer and Nutrition-Norfolk in relation to phytoestrogen intake derived from an improved database.

Ward HA, Kuhnle GG, Mulligan AA, Lentjes MA, Luben RN, and Khaw KT

The American Journal of Clinical Nutrition. Dec 2009

(DOI : 10.3945/ajcn.2009.28282)

Phytoestrogen exposure, polymorphisms in COMT, CYP19, ESR1, and SHBG genes, and their associations with prostate cancer risk

Wareham NJ, Bingham SA, Day NE, Dunning AM, Khaw KT, Low YL, Luben RN, Mulligan AA, Welch AA, Taylor JI, and Grace PB

Nutrition and cancer. Nov 2009

(DOI : 10.1207/s15327914nc5601_5)

Cumulative effects and predictive value of common obesity-susceptibility variants identified by genome-wide association studies.

Li S, Zhao JH, Luan J, Luben RN, Rodwell SA, Khaw KT, Ong KK, Wareham NJ, and Loos RJ

The American Journal of Clinical Nutrition. Oct 2009

(DOI : 10.3945/ajcn.2009.28403)

Dietary, lifestyle and clinicopathological factors associated with BRAF and K-ras mutations arising in distinct subsets of colorectal cancers in the EPIC Norfolk study.

Naguib A, Mitrou PN, Gay LJ, Cooke JC, Luben RN, Ball RY, McTaggart A, Arends MJ, and Rodwell SA

BMC cancer. Oct 2009

(DOI : 10.1186/1471-2407-10-99)

MGMT Ile143Val polymorphism, dietary factors and the risk of breast, colorectal and prostate cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC)-Norfolk study.

Loh YH, Mitrou PN, Bowman R, Wood A, Jeffery H, Luben RN, Lentjes MA, Khaw KT, and Rodwell SA

DNA repair. Sep 2009

(DOI : 10.1016/j.dnarep.2010.01.002)

Baseline alcohol consumption, type of alcoholic beverage and risk of colorectal cancer in the European Prospective Investigation into Cancer and Nutrition-Norfolk study.

Park JY, Mitrou PN, Dahm CC, Luben RN, Wareham NJ, Khaw KT, and Rodwell SA

Cancer Epidemiology. Jul 2009

(DOI : 10.1016/j.canep.2009.10.015)

Association between type of dietary fish and seafood intake and the risk of incident type 2 diabetes: the European prospective investigation of cancer (EPIC)-Norfolk cohort study.

Patel PS, Sharp SJ, Luben RN, Khaw KT, Bingham SA, Wareham NJ, and Forouhi NG

Diabetes care. Jul 2009

(DOI : 10.2337/dc09-0116)

No evidence that social stress is associated with breast cancer incidence.

Surtees PG, Wainwright NW, Luben RN, Khaw KT, and Bingham SA

Breast cancer research and treatment. Jun 2009

(DOI : 10.1007/s10549-009-0454-6)

Respiratory function as a marker of bone health and fracture risk in an older population.

Moayyeri A, Bingham SA, Luben RN, Wareham NJ, and Khaw KT

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. Apr 2009

(DOI : 10.1359/jbmr.081231)

Is QUS or DXA better for predicting the 10-year absolute risk of fracture?

Moayyeri A, Kaptoge S, Dalzell N, Bingham S, Luben RN, Wareham NJ, Reeve J, and Khaw KT

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. Mar 2009

(DOI : 10.1359/jbmr.090212)

Combined effect of health behaviours and risk of first ever stroke in 20,040 men and women over 11 years' follow-up in Norfolk cohort of European Prospective Investigation of Cancer (EPIC Norfolk): prospective population study.

Myint PK, Luben RN, Wareham NJ, Bingham SA, and Khaw KT

BMJ (Clinical research ed.). Feb 2009

(DOI : 10.1136/bmj.b349)

The Short-Form Six-Dimension utility index predicted mortality in the European Prospective Investigation into Cancer-Norfolk prospective population-based study.

Myint PK, Smith RD, Luben RN, Surtees PG, Wainwright NW, Wareham NJ, Bingham SA, and Khaw KT

Journal of clinical epidemiology. Jan 2009

(DOI : 10.1016/j.jclinepi.2009.05.002)

Identification of common variants in the SHBG gene affecting sex hormone-binding globulin levels and breast cancer risk in postmenopausal women.

Thompson DJ, Healey CS, Baynes C, Kalmyrzaev B, Ahmed S, Dowsett M, Folkerd E, Luben RN, Cox D, Ballinger D, Pharoah PD, Ponder BA, Dunning AM, Easton DF, and Studies in Epidemiology and Risks of Cancer Heredity Team

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. Dec 2008

(DOI : 10.1158/1055-9965.EPI-08-0734)

Effect of age and sex on the relationship between different socioeconomic indices and self-reported functional health in the EPIC-Norfolk population-based study.

Myint PK, Luben RN, Surtees PG, Wainwright NW, Bingham SA, Wareham NJ, and Khaw KT

Annals of Epidemiology. Oct 2008

(DOI : 10.1016/j.annepidem.2009.02.003)

Estimation of absolute fracture risk among middle-aged and older men and women: the EPIC-Norfolk population cohort study.

Moayyeri A, Kaptoge S, Luben RN, Wareham NJ, Bingham S, Reeve J, and Khaw KT

European Journal of Epidemiology. Oct 2008

(DOI : 10.1007/s10654-009-9337-8)

Prospective association between emotional health and clinical evidence of Parkinson's disease.

Ishihara-Paul L, Wainwright NW, Khaw KT, Luben RN, Welch AA, Day NE, Brayne C, and Surtees PG

European journal of neurology. Sep 2008

(DOI : 10.1111/j.1468-1331.2008.02299.x)

Risk factors for first-ever stroke in the EPIC-Norfolk prospective population-based study.

Myint PK, Sinha S, Luben RN, Bingham SA, Wareham NJ, and Khaw KT

European journal of cardiovascular prevention and rehabilitation : official journal of the European Society of Cardiology, Working Groups on Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology. Sep 2008

(DOI : 10.1097/HJR.0b013e32830fe465)

Major depression, C-reactive protein, and incident ischemic heart disease in healthy men and women.

Surtees PG, Wainwright NW, Boekholdt SM, Luben RN, Wareham NJ, and Khaw KT

Psychosomatic medicine. Aug 2008

(DOI : 10.1097/PSY.0b013e318183acd5)

No association between APOE and major depressive disorder in a community sample of 17,507 adults.

Surtees PG, Wainwright NW, Bowman R, Luben RN, Wareham NJ, Khaw KT, and Bingham SA

Journal of psychiatric research. Aug 2008

(DOI : 10.1016/j.jpsychires.2008.12.001)

Sense of coherence, lifestyle choices and mortality.

Wainwright NW, Surtees PG, Welch AA, Luben RN, Khaw KT, and Bingham SA

Journal of Epidemiology and Community Health. Aug 2008

(DOI : 10.1136/jech.2007.066464)

The effect of including quantitative heel ultrasound in models for estimation of 10-year absolute risk of fracture.

Moayyeri A, Kaptoge S, Dalzell N, Luben RN, Wareham NJ, Bingham S, Reeve J, and Khaw KT

Bone. Aug 2008

(DOI : 10.1016/j.bone.2009.05.001)

Genome-wide association study identifies eight loci associated with blood pressure.

Newton-Cheh C, Johnson T, Gateva V, Tobin MD, Bochud M, Coin L, Najjar SS, Zhao JH, Heath SC, Eyheramendy S, Papadakis K, Voight BF, Scott LJ, Zhang F, Farrall M, Tanaka T, Wallace C, Chambers JC, Khaw KT, Nilsson P, van der Harst P, Polidoro S, Grobbee DE, Onland-Moret NC, Bots ML, Wain LV, Elliott KS, Teumer A, Luan J, Lucas G, Kuusisto J, Burton PR, Hadley D, McArdle WL, Brown M, Dominiczak A, Newhouse SJ, Samani NJ, Webster J, Zeggini E, Beckmann JS, Bergmann S, Lim N, Song K, Vollenweider P, Waeber G, Waterworth DM, Yuan X, Groop L, Orho-Melander M, Allione A, Di Gregorio A, Guarrera S, Panico S, Ricceri F, Romanazzi V, Sacerdote C, Vineis P, Barroso I, Sandhu MS, Luben RN, Crawford GJ, Jousilahti P, Perola M, Boehnke M, Bonnycastle LL, Collins FS, Jackson AU, Mohlke KL, Stringham HM, Valle TT, Willer CJ, Bergman RN, Morken MA, Döring A, Gieger C, Illig T, Meitinger T, Org E, Pfeufer A, Wichmann HE, Kathiresan S, Marrugat J, O'Donnell CJ, Schwartz SM, Siscovick DS, Subirana I, Freimer NB, Hartikainen AL, McCarthy MI, O'Reilly PF, Peltonen L, Pouta A, de Jong PE, Snieder H, van Gilst WH, Clarke R, Goel A, Hamsten A, Peden JF, Seedorf U, Syvänen AC, Tognoni G, Lakatta EG, Sanna S, Scheet P, Schlessinger D, Scuteri A, Dörr M, Ernst F, Felix SB, Homuth G, Lorbeer R, Reffelmann T, Rettig R, Völker U, Galan P, Gut IG, Hercberg S, Lathrop GM, Zelenika D, Deloukas P, Soranzo N, Williams FM, Zhai G, Salomaa V, Laakso M, Elosua R, Forouhi NG, Völzke H, Uiterwaal CS, van der Schouw YT, Numans ME, Matullo G, Navis G, Berglund G, Bingham SA, Kooner JS, Connell JM, Bandinelli S, Ferrucci L, Watkins H, Spector TD, Tuomilehto J, Altshuler D, Strachan DP, Laan M, Meneton P, Wareham NJ, Uda M, Järvelin MR, Mooser V, Melander O, Loos RJ, Elliott P, Abecasis GR, Caulfield M, and Munroe PB

Nature genetics. Aug 2008

(DOI : 10.1038/ng.361)

Six new loci associated with body mass index highlight a neuronal influence on body weight regulation.

Willer CJ, Speliotes EK, Loos RJ, Li S, Lindgren CM, Heid IM, Berndt SI, Elliott AL, Jackson AU, Lamina C, Lettre G, Lim N, Lyon HN, McCarroll SA, Papadakis K, Qi L, Randall JC, Roccasecca RM, Sanna S, Scheet P, Weedon MN, Wheeler E, Zhao JH, Jacobs LC, Prokopenko I, Soranzo N, Tanaka T, Timpson NJ, Almgren P, Bennett A, Bergman RN, Bingham SA, Bonnycastle LL, Brown M, Burtt NP, Chines P, Coin L, Collins FS, Connell JM, Cooper C, Smith GD, Dennison EM, Deodhar P, Elliott P, Erdos MR, Estrada K, Evans DM, Gianniny L, Gieger C, Gillson CJ, Guiducci C, Hackett R, Hadley D, Hall AS, Havulinna AS, Hebebrand J, Hofman A, Isomaa B, Jacobs KB, Johnson T, Jousilahti P, Jovanovic Z, Khaw KT, Kraft P, Kuokkanen M, Kuusisto J, Laitinen J, Lakatta EG, Luan J, Luben RN, Mangino M, McArdle WL, Meitinger T, Mulas A, Munroe PB, Narisu N, Ness AR, Northstone K, O'Rahilly S, Purmann C, Rees MG, Ridderstråle M, Ring SM, Rivadeneira F, Ruokonen A, Sandhu MS, Saramies J, Scott LJ, Scuteri A, Silander K, Sims MA, Song K, Stephens J, Stevens S, Stringham HM, Tung YC, Valle TT, van Duijn CM, Vimaleswaran KS, Vollenweider P, Waeber G, Wallace C, Watanabe RM, Waterworth DM, Watkins N, Witteman JC, Zeggini E, Zhai G, Zillikens MC, Altshuler D, Caulfield MJ, Chanock SJ, Farooqi IS, Ferrucci L, Guralnik JM, Hattersley AT, Hu FB, Järvelin MR, Laakso M, Mooser V, Ong KK, Ouwehand WH, Salomaa V, Samani NJ, Spector TD, Tuomi T, Tuomilehto J, Uda M, Uitterlinden AG, Wareham NJ, Deloukas P, Frayling TM, Groop LC, Hayes RB, Hunter DJ, Mohlke KL, Peltonen L, Schlessinger D, Strachan DP, Wichmann HE, McCarthy MI, Boehnke M, Barroso I, Abecasis GR, and Hirschhorn JN

Nature genetics. Jul 2008

(DOI : 10.1038/ng.287)

Factor VII, blood lipids and fat intake: gene-nutrient interaction and risk of coronary heart disease with the factor VII R353Q polymorphism.

Bowman R, Joosen AM, Welch AA, Luben RN, Khaw KT, Wareham NJ, and Bingham SA

European Journal of Clinical Nutrition. Apr 2008

(DOI : 10.1038/ejcn.2008.28)

Accuracy of death certification and hospital record linkage for identification of incident stroke.

Sinha S, Myint PK, Luben RN, and Khaw KT

BMC Medical Research Methodology. Apr 2008

(DOI : 10.1186/1471-2288-8-74)

Psychological distress, major depressive disorder, and risk of stroke.

Surtees PG, Wainwright NW, Luben RN, Wareham NJ, Bingham SA, and Khaw KT

Neurology. Mar 2008

(DOI : 10.1212/01.wnl.0000304109.18563.81)

Depression and ischemic heart disease mortality: evidence from the EPIC-Norfolk United Kingdom prospective cohort study.

Surtees PG, Wainwright NW, Luben RN, Wareham NJ, Bingham SA, and Khaw KT

The American journal of psychiatry. Feb 2008

(DOI : 10.1176/appi.ajp.2007.07061018)

Plasma vitamin C concentrations predict risk of incident stroke over 10 y in 20 649 participants of the European Prospective Investigation into Cancer Norfolk prospective population study.

Myint PK, Luben RN, Welch AA, Bingham SA, Wareham NJ, and Khaw KT

The American Journal of Clinical Nutrition. Jan 2008

(DOI : 10.1093/ajcn/87.1.64)

Energy intake at breakfast and weight change: prospective study of 6,764 middle-aged men and women.

Purslow LR, Sandhu MS, Forouhi N, Young EH, Luben RN, Welch AA, Khaw KT, Bingham SA, and Wareham NJ

American Journal of Epidemiology. Dec 2007

(DOI : 10.1093/aje/kwm309)

Physical health-related quality of life predicts stroke in the EPIC-Norfolk.

Myint PK, Surtees PG, Wainwright NW, Luben RN, Welch AA, Bingham SA, Wareham NJ, and Khaw KT

Neurology. Dec 2007

(DOI : 10.1212/01.wnl.0000296010.21252.78)

Common variants near MC4R are associated with fat mass, weight and risk of obesity.

Loos RJ, Lindgren CM, Li S, Wheeler E, Zhao JH, Prokopenko I, Inouye M, Freathy RM, Attwood AP, Beckmann JS, Berndt SI, Jacobs KB, Chanock SJ, Hayes RB, Bergmann S, Bennett AJ, Bingham SA, Bochud M, Brown M, Cauchi S, Connell JM, Cooper C, Smith GD, Day I, Dina C, De S, Dermitzakis ET, Doney AS, Elliott KS, Elliott P, Evans DM, Sadaf Farooqi I, Froguel P, Ghori J, Groves CJ, Gwilliam R, Hadley D, Hall AS, Hattersley AT, Hebebrand J, Heid IM, Lamina C, Gieger C, Illig T, Meitinger T, Wichmann HE, Herrera B, Hinney A, Hunt SE, Järvelin MR, Johnson T, Jolley JD, Karpe F, Keniry A, Khaw KT, Luben RN, Mangino M, Marchini J, McArdle WL, McGinnis R, Meyre D, Munroe PB, Morris AD, Ness AR, Neville MJ, Nica AC, Ong KK, O'Rahilly S, Owen KR, Palmer CN, Papadakis K, Potter S, Pouta A, Qi L, Randall JC, Rayner NW, Ring SM, Sandhu MS, Scherag A, Sims MA, Song K, Soranzo N, Speliotes EK, Syddall HE, Teichmann SA, Timpson NJ, Tobias JH, Uda M, Vogel CI, Wallace C, Waterworth DM, Weedon MN, Willer CJ, Wraight, Yuan X, Zeggini E, Hirschhorn JN, Strachan DP, Ouwehand WH, Caulfield MJ, Samani NJ, Frayling TM, Vollenweider P, Waeber G, Mooser V, Deloukas P, McCarthy MI, Wareham NJ, Barroso I, Jacobs KB, Chanock SJ, Hayes RB, Lamina C, Gieger C, Illig T, Meitinger T, Wichmann HE, Kraft P, Hankinson SE, Hunter DJ, Hu FB, Lyon HN, Voight BF, Ridderstråle M, Groop L, Scheet P, Sanna S, Abecasis GR, Albai G, Nagaraja R, Schlessinger D, Jackson AU, Tuomilehto J, Collins FS, Boehnke M, and Mohlke KL

Nature genetics. Nov 2007

(DOI : 10.1038/ng.140)

Measured height loss predicts fractures in middle-aged and older men and women: the EPIC-Norfolk prospective population study.

Moayyeri A, Luben RN, Bingham SA, Welch AA, Wareham NJ, and Khaw KT

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. Nov 2007

(DOI : 10.1359/jbmr.071106)

Apolipoprotein E polymorphisms, dietary fat and fibre, and serum lipids: the EPIC Norfolk study.

Wu K, Bowman R, Welch AA, Luben RN, Wareham NJ, Khaw KT, and Bingham SA

European heart journal. Nov 2007

(DOI : 10.1093/eurheartj/ehm482)

Healthy lifestyle choices: could sense of coherence aid health promotion?

Wainwright NW, Surtees PG, Welch AA, Luben RN, Khaw KT, and Bingham SA

Journal of Epidemiology and Community Health. Sep 2007

(DOI : 10.1136/jech.2006.056275)

Socioeconomic position and risk of short-term weight gain: prospective study of 14,619 middle-aged men and women.

Purslow LR, Young EH, Wareham NJ, Forouhi N, Brunner EJ, Luben RN, Welch AA, Khaw KT, Bingham SA, and Sandhu MS

BMC Public Health. Jul 2007

(DOI : 10.1186/1471-2458-8-112)

Self-reported mental health-related quality of life and mortality in men and women in the European Prospective Investigation into Cancer (EPIC-Norfolk): a prospective population study.

Myint PK, Luben RN, Surtees PG, Wainwright NW, Welch AA, Bingham SA, Wareham NJ, Smith RD, Harvey IM, and Khaw KT

Psychosomatic medicine. Jun 2007

(DOI : 10.1097/psy.0b013e318068fcd4)

Physical activity and fibrinogen concentrations in 23,201 men and women in the EPIC-Norfolk population-based study.

Myint PK, Luben RN, Wareham NJ, Welch AA, Bingham SA, and Khaw KT

Atherosclerosis. Feb 2007

(DOI : 10.1016/j.atherosclerosis.2007.09.021)

Common variants in the ATM, BRCA1, BRCA2, CHEK2 and TP53 cancer susceptibility genes are unlikely to increase breast cancer risk.

Baynes C, Healey CS, Pooley KA, Scollen S, Luben RN, Thompson DJ, Pharoah PD, Easton DF, Ponder BA, Dunning AM, and SEARCH breast cancer study

Breast cancer research : BCR. Jan 2007

(DOI : 10.1186/bcr1669)

Fruit and vegetable consumption and self-reported functional health in men and women in the European Prospective Investigation into Cancer-Norfolk (EPIC-Norfolk): a population-based cross-sectional study.

Myint PK, Welch AA, Bingham SA, Surtees PG, Wainwright NW, Luben RN, Wareham NJ, Smith RD, Harvey IM, Day NE, and Khaw KT

Public Health Nutrition. Jan 2007

(DOI : 10.1017/S1368980007222608)

Glycated hemoglobin and risk of stroke in people without known diabetes in the European Prospective Investigation into Cancer (EPIC)-Norfolk prospective population study: a threshold relationship?

Myint PK, Sinha S, Wareham NJ, Bingham SA, Luben RN, Welch AA, and Khaw KT

Stroke. Jan 2007

(DOI : 10.1161/01.STR.0000254549.75763.5f)

Physical activity, C-reactive protein levels and the risk of future coronary artery disease in apparently healthy men and women: the EPIC-Norfolk prospective population study

Wareham NJ, Bingham SA, Boekholdt SM, Day NE, Khaw KT, Luben RN, Peters RJ, and Sandhu MS

European Journal of Preventive Cardiology. Dec 2006

(DOI : 10.1097/01.hjr.0000209811.97948.07)

Plasma levels of plant sterols and the risk of coronary artery disease: the prospective EPIC-Norfolk Population Study

Wareham NJ, Boekholdt SM, Kastelein JJ, Khaw KT, Luben RN, Vissers PAJ, Pinedo S, Von Bergmann K, Elharchaoui K, and Lütjohann D

Journal of lipid research. Oct 2006

(DOI : 10.1194/jlr.M600371-JLR200)

Habitual fish consumption and risk of incident stroke: the European Prospective Investigation into Cancer (EPIC)-Norfolk prospective population study.

Myint PK, Welch AA, Bingham SA, Luben RN, Wareham NJ, Day NE, and Khaw KT

Public Health Nutrition. Oct 2006

(DOI : 10.1017/phn2006942)

Implications of gene-environment interaction in studies of gene variants in breast cancer: an example of dietary isoflavones and the D356N polymorphism in the sex hormone-binding globulin gene.

Low YL, Dunning AM, Dowsett M, Luben RN, Khaw KT, Wareham NJ, and Bingham SA

Cancer research. Sep 2006

(DOI : 10.1158/0008-5472.CAN-06-2432)

Combined work and leisure physical activity and risk of stroke in men and women in the European prospective investigation into Cancer-Norfolk Prospective Population Study.

Myint PK, Luben RN, Wareham NJ, Welch AA, Bingham SA, Day NE, and Khaw KT

Neuroepidemiology. Sep 2006

(DOI : 10.1159/000095551)

Associations among mammographic density, circulating sex hormones, and polymorphisms in sex hormone metabolism genes in postmenopausal women.

Warren R, Skinner J, Sala E, Denton E, Dowsett M, Folkerd E, Healey CS, Dunning A, Doody D, Ponder B, Luben RN, Day NE, and Easton D

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. Aug 2006

(DOI : 10.1158/1055-9965.EPI-05-0828)

Obesity indices and self-reported functional health in men and women in the EPIC-Norfolk.

Myint PK, Welch AA, Luben RN, Wainwright NW, Surtees PG, Bingham SA, Wareham NJ, Smith RD, Harvey IM, and Khaw KT

Obesity (Silver Spring, Md.). Jul 2006

(DOI : 10.1038/oby.2006.102)

Dietary antioxidants and asthma in adults.

Patel BD, Welch AA, Bingham SA, Luben RN, Day NE, Khaw KT, Lomas DA, and Wareham NJ

Thorax. Feb 2006

(DOI : 10.1136/thx.2004.024935)

Modifiable lifestyle behaviors and functional health in the European Prospective Investigation into Cancer (EPIC)-Norfolk population study.

Myint PK, Surtees PG, Wainwright NW, Wareham NJ, Bingham SA, Luben RN, Welch AA, Smith RD, Harvey IM, and Khaw KT

Preventive medicine. Jan 2006

(DOI : 10.1016/j.ypmed.2006.09.007)

Polymorphisms in the CYP19 gene may affect the positive correlations between serum and urine phytoestrogen metabolites and plasma androgen concentrations in men.

Low YL, Taylor JI, Grace PB, Dowsett M, Folkerd E, Doody D, Dunning AM, Scollen S, Mulligan AA, Welch AA, Luben RN, Khaw KT, Day NE, Wareham NJ, and Bingham SA

The Journal of nutrition. Oct 2005

(DOI : 10.1093/jn/135.11.2680)

Respiratory function and self-reported functional health: EPIC-Norfolk population study.

Myint PK, Luben RN, Surtees PG, Wainwright NW, Welch AA, Bingham SA, Wareham NJ, Day NE, and Khaw KT

The European respiratory journal. Sep 2005

(DOI : 10.1183/09031936.05.00023605)

Smoking predicts long-term mortality in stroke: The European Prospective Investigation into Cancer (EPIC)-Norfolk prospective population study.

Myint PK, Welch AA, Bingham SA, Luben RN, Wareham NJ, Day NE, and Khaw KT

Preventive Medicine . Aug 2005

(DOI : 10.1016/j.ypmed.2005.11.014)

Effect of age on the relationship of occupational social class with prevalence of modifiable cardiovascular risk factors and cardiovascular diseases. A population-based cross-sectional study from European Prospective Investigation into Cancer - Norfolk (EPIC-Norfolk).

Myint PK, Luben RN, Welch AA, Bingham SA, Wareham NJ, and Khaw KT

Gerontology. Aug 2005

(DOI : 10.1159/000089826)

Relation between self-reported physical functional health and chronic disease mortality in men and women in the European Prospective Investigation into Cancer (EPIC-Norfolk): a prospective population study.

Myint PK, Luben RN, Surtees PG, Wainwright NW, Welch AA, Bingham SA, Day NE, Wareham NJ, and Khaw KT

Annals of Epidemiology. Apr 2005

(DOI : 10.1016/j.annepidem.2005.04.005)

Fibrinogen and cigarette smoking in men and women in the European Prospective Investigation into Cancer in Norfolk (EPIC-Norfolk) population.

Sinha S, Luben RN, Welch A, Bingham S, Wareham NJ, Day NE, and Khaw KT

(DOI : 10.1097/01.hjr.0000140719.09768.e2)

Common variation in EMSY and risk of breast and ovarian cancer: a case-control study using HapMap tagging SNPs.

Benusiglio PR, Lesueur F, Luccarini C, McIntosh J, Luben RN, Smith P, Dunning A, Easton DF, Ponder BA, and Pharoah PD

BMC cancer. Mar 2005

(DOI : 10.1186/1471-2407-5-81)

Phytoestrogen exposure correlation with plasma estradiol in postmenopausal women in European Prospective Investigation of Cancer and Nutrition-Norfolk may involve diet-gene interactions.

Low YL, Taylor JI, Grace PB, Dowsett M, Scollen S, Dunning AM, Mulligan AA, Welch AA, Luben RN, Khaw KT, Day NE, Wareham NJ, and Bingham SA

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. Jan 2005

(DOI : 14/1/213)

STK15 polymorphisms and association with risk of invasive ovarian cancer.

Dicioccio RA, Song H, Waterfall C, Kimura MT, Nagase H, McGuire V, Hogdall E, Shah MN, Luben RN, Easton DF, Jacobs IJ, Ponder BA, Whittemore AS, Gayther SA, Pharoah PD, and Kruger-Kjaer S

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. Oct 2004

(DOI : 13/10/1589)

Childhood smoking is an independent risk factor for obstructive airways disease in women.

Patel BD, Luben RN, Welch AA, Bingham SA, Khaw KT, Day NE, Lomas DA, and Wareham NJ

Thorax. Jul 2004

(DOI : 10.1136/thx.2003.010215)

Polymorphisms associated with circulating sex hormone levels in postmenopausal women.

Dunning AM, Dowsett M, Healey CS, Tee L, Luben RN, Folkerd E, Novik KL, Kelemen L, Ogata S, Pharoah PD, Easton DF, Day NE, and Ponder BA

Journal of the National Cancer Institute. Jun 2004

(DOI : 10.1093/jnci/djh167)

Phytoestrogen concentrations in serum and spot urine as biomarkers for dietary phytoestrogen intake and their relation to breast cancer risk in European prospective investigation of cancer and nutrition-norfolk.

Grace PB, Taylor JI, Low YL, Luben RN, Mulligan AA, Botting NP, Dowsett M, Welch AA, Khaw KT, Wareham NJ, Day NE, and Bingham SA

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. May 2004

(DOI : 13/5/698)

Habitual fish consumption and glycated haemoglobin: the EPIC-Norfolk study.

Harding AH, Day NE, Khaw KT, Bingham SA, Luben RN, Welsh A, and Wareham NJ

European Journal of Clinical Nutrition. Jan 2004

(DOI : 10.1038/sj.ejcn.1601779)

Smoking status and differential white cell count in men and women in the EPIC-Norfolk population.

Smith MR, Kinmonth AL, Luben RN, Bingham S, Day NE, Wareham NJ, Welch A, and Khaw KT

Atherosclerosis. Aug 2003

(DOI : 10.1016/s0021-9150(03)00200-4)

A transforming growth factorbeta1 signal peptide variant increases secretion in vitro and is associated with increased incidence of invasive breast cancer.

Dunning AM, Ellis PD, McBride S, Kirschenlohr HL, Healey CS, Kemp PR, Luben RN, Chang-Claude J, Mannermaa A, Kataja V, Pharoah PD, Easton DF, Ponder BA, and Metcalfe JC