EPIC-Norfolk Publications Database

Large scale phenotype imputation and in vivo functional validation implicate ADAMTS14 as an adiposity gene.

Kentistou KA, Luan J, Wittemans LBL, Hambly C, Klaric L, Kutalik Z, Speakman JR, Wareham NJ, Kendall TJ, Langenberg C, Wilson JF, Joshi PK, and Morton NM

Nature communications. Jan 2023

(DOI : 10.1038/s41467-022-35563-0)

HOTAIR interacts with PRC2 complex regulating the regional preadipocyte transcriptome and human fat distribution.

Kuo FC, Neville MJ, Sabaratnam R, Wesolowska-Andersen A, Phillips D, Wittemans LBL, van Dam AD, Loh NY, Todorčević M, Denton N, Kentistou KA, Joshi PK, Christodoulides C, Langenberg C, Collas P, Karpe F, and Pinnick KE

Cell reports. Jul 2022

(DOI : 10.1016/j.celrep.2022.111136)

Using genetic variation to disentangle the complex relationship between food intake and health outcomes.

Pirastu N, McDonnell C, Grzeszkowiak EJ, Mounier N, Imamura F, Merino J, Day FR, Zheng J, Taba N, Concas MP, Repetto L, Kentistou KA, Robino A, Esko T, Joshi PK, Fischer K, Ong KK, Gaunt TR, Kutalik Z, Perry JRB, and Wilson JF

PLoS genetics. Jun 2022

(DOI : 10.1371/journal.pgen.1010162)